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Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations.
Sakornsakolpat P, Prokopenko D, Lamontagne M, Reeve NF, Guyatt AL, Jackson VE, Shrine N, Qiao D, Bartz TM, Kim DK, Lee MK, Latourelle JC, Li X, Morrow JD, Obeidat M, Wyss AB, Bakke P, Barr RG, Beaty TH, Belinsky SA, Brusselle GG, Crapo JD, de Jong K, DeMeo DL, Fingerlin TE, Gharib SA, Gulsvik A, Hall IP, Hokanson JE, Kim WJ, Lomas DA, London SJ, Meyers DA, O'Connor GT, Rennard SI, Schwartz DA, Sliwinski P, Sparrow D, Strachan DP, Tal-Singer R, Tesfaigzi Y, Vestbo J, Vonk JM, Yim JJ, Zhou X, Bossé Y, Manichaikul A, Lahousse L, Silverman EK, Boezen HM, Wain LV, Tobin MD, Hobbs BD, Cho MH; SpiroMeta Consortium; International COPD Genetics Consortium. Sakornsakolpat P, et al. Among authors: tesfaigzi y. Nat Genet. 2019 Mar;51(3):494-505. doi: 10.1038/s41588-018-0342-2. Epub 2019 Feb 25. Nat Genet. 2019. PMID: 30804561 Free PMC article.
Activation of CD8+ T Cells in Chronic Obstructive Pulmonary Disease Lung.
Villaseñor-Altamirano AB, Jain D, Jeong Y, Menon JA, Kamiya M, Haider H, Manandhar R, Sheikh MDA, Athar H, Merriam LT, Ryu MH, Sasaki T, Castaldi PJ, Rao DA, Sholl LM, Vivero M, Hersh CP, Zhou X, Veerkamp J, Yun JH, Kim EY; MassGeneralBrigham - Bayer Pulmonary Drug Discovery Laboratory. Villaseñor-Altamirano AB, et al. Am J Respir Crit Care Med. 2023 Dec 1;208(11):1177-1195. doi: 10.1164/rccm.202305-0924OC. Am J Respir Crit Care Med. 2023. PMID: 37756440
Bik promotes proteasomal degradation to control low-grade inflammation.
Mebratu YA, Jones JT, Liu C, Negasi ZH, Rahman M, Rojas-Quintero J, O'Connor GT, Gao W, Dupuis J, Cho MH, Litonjua AA, Randell S, Tesfaigzi Y. Mebratu YA, et al. Among authors: tesfaigzi y. J Clin Invest. 2023 Dec 19;134(4):e170594. doi: 10.1172/JCI170594. J Clin Invest. 2023. PMID: 38113109 Free PMC article.
Circulating biomarkers of airflow limitation across the life span.
Zhai J, Voraphani N, Imboden M, Keidel D, Liu C, Stern DA, Venker C, Petersen H, Bosco A, Sherrill DL, Morgan WJ, Tesfaigzi Y, Probst-Hensch NM, Martinez FD, Halonen M, Guerra S. Zhai J, et al. Among authors: tesfaigzi y. J Allergy Clin Immunol. 2024 Jan 20:S0091-6749(24)00037-X. doi: 10.1016/j.jaci.2023.12.026. Online ahead of print. J Allergy Clin Immunol. 2024. PMID: 38253260
CC16 augmentation reduces exaggerated COPD-like disease in Cc16-deficient mice.
Rojas-Quintero J, Laucho-Contreras ME, Wang X, Fucci QA, Burkett PR, Kim SJ, Zhang D, Tesfaigzi Y, Li Y, Bhashyam AR, Li Z, Khamas H, Celli B, Pilon AL, Polverino F, Owen CA. Rojas-Quintero J, et al. Among authors: tesfaigzi y. JCI Insight. 2023 Mar 22;8(6):e130771. doi: 10.1172/jci.insight.130771. JCI Insight. 2023. PMID: 36787195 Free PMC article.
Single-cell transcriptomics reveal a hyperacute cytokine and immune checkpoint axis after cardiac arrest in patients with poor neurological outcome.
Tamura T, Cheng C, Chen W, Merriam LT, Athar H, Kim YH, Manandhar R, Amir Sheikh MD, Pinilla-Vera M, Varon J, Hou PC, Lawler PR, Oldham WM, Seethala RR, Tesfaigzi Y; Immunology of Cardiac Arrest Network (I-CAN); Weissman AJ, Baron RM, Ichinose F, Berg KM, Bohula EA, Morrow DA, Chen X, Kim EY. Tamura T, et al. Among authors: tesfaigzi y. Med. 2023 Jul 14;4(7):432-456.e6. doi: 10.1016/j.medj.2023.05.003. Epub 2023 May 30. Med. 2023. PMID: 37257452
151 results