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Glial-conditional deletion of aquaporin-4 (Aqp4) reduces blood-brain water uptake and confers barrier function on perivascular astrocyte endfeet.
Haj-Yasein NN, Vindedal GF, Eilert-Olsen M, Gundersen GA, Skare Ø, Laake P, Klungland A, Thorén AE, Burkhardt JM, Ottersen OP, Nagelhus EA. Haj-Yasein NN, et al. Among authors: thoren ae. Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17815-20. doi: 10.1073/pnas.1110655108. Epub 2011 Oct 11. Proc Natl Acad Sci U S A. 2011. PMID: 21990350 Free PMC article.
Deletion of aquaporin-4 improves capillary blood flow distribution in brain edema.
Bordoni L, Thoren AE, Gutiérrez-Jiménez E, Åbjørsbråten KS, Bjørnstad DM, Tang W, Stern M, Østergaard L, Nagelhus EA, Frische S, Ottersen OP, Enger R. Bordoni L, et al. Among authors: thoren ae. Glia. 2023 Nov;71(11):2559-2572. doi: 10.1002/glia.24439. Epub 2023 Jul 13. Glia. 2023. PMID: 37439315 Free PMC article.
Role of aquaporin-4 polarization in extracellular solute clearance.
Bojarskaite L, Nafari S, Ravnanger AK, Frey MM, Skauli N, Åbjørsbråten KS, Roth LC, Amiry-Moghaddam M, Nagelhus EA, Ottersen OP, Bogen IL, Thoren AE, Enger R. Bojarskaite L, et al. Among authors: thoren ae. Fluids Barriers CNS. 2024 Mar 26;21(1):28. doi: 10.1186/s12987-024-00527-7. Fluids Barriers CNS. 2024. PMID: 38532513 Free PMC article.
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