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NAD+ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair.
Fang EF, Kassahun H, Croteau DL, Scheibye-Knudsen M, Marosi K, Lu H, Shamanna RA, Kalyanasundaram S, Bollineni RC, Wilson MA, Iser WB, Wollman BN, Morevati M, Li J, Kerr JS, Lu Q, Waltz TB, Tian J, Sinclair DA, Mattson MP, Nilsen H, Bohr VA. Fang EF, et al. Among authors: tian j. Cell Metab. 2016 Oct 11;24(4):566-581. doi: 10.1016/j.cmet.2016.09.004. Cell Metab. 2016. PMID: 27732836 Free PMC article.
RECQL4 localizes to mitochondria and preserves mitochondrial DNA integrity.
Croteau DL, Rossi ML, Canugovi C, Tian J, Sykora P, Ramamoorthy M, Wang ZM, Singh DK, Akbari M, Kasiviswanathan R, Copeland WC, Bohr VA. Croteau DL, et al. Among authors: tian j. Aging Cell. 2012 Jun;11(3):456-66. doi: 10.1111/j.1474-9726.2012.00803.x. Epub 2012 Mar 2. Aging Cell. 2012. PMID: 22296597 Free PMC article.
DNA polymerase β deficiency leads to neurodegeneration and exacerbates Alzheimer disease phenotypes.
Sykora P, Misiak M, Wang Y, Ghosh S, Leandro GS, Liu D, Tian J, Baptiste BA, Cong WN, Brenerman BM, Fang E, Becker KG, Hamilton RJ, Chigurupati S, Zhang Y, Egan JM, Croteau DL, Wilson DM 3rd, Mattson MP, Bohr VA. Sykora P, et al. Among authors: tian j. Nucleic Acids Res. 2015 Jan;43(2):943-59. doi: 10.1093/nar/gku1356. Epub 2014 Dec 30. Nucleic Acids Res. 2015. PMID: 25552414 Free PMC article.
DNA Polymerase Beta Participates in Mitochondrial DNA Repair.
Sykora P, Kanno S, Akbari M, Kulikowicz T, Baptiste BA, Leandro GS, Lu H, Tian J, May A, Becker KA, Croteau DL, Wilson DM 3rd, Sobol RW, Yasui A, Bohr VA. Sykora P, et al. Among authors: tian j. Mol Cell Biol. 2017 Jul 28;37(16):e00237-17. doi: 10.1128/MCB.00237-17. Print 2017 Aug 15. Mol Cell Biol. 2017. PMID: 28559431 Free PMC article.
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12,216 results
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