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Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations.
Kowalski MH, Qian H, Hou Z, Rosen JD, Tapia AL, Shan Y, Jain D, Argos M, Arnett DK, Avery C, Barnes KC, Becker LC, Bien SA, Bis JC, Blangero J, Boerwinkle E, Bowden DW, Buyske S, Cai J, Cho MH, Choi SH, Choquet H, Cupples LA, Cushman M, Daya M, de Vries PS, Ellinor PT, Faraday N, Fornage M, Gabriel S, Ganesh SK, Graff M, Gupta N, He J, Heckbert SR, Hidalgo B, Hodonsky CJ, Irvin MR, Johnson AD, Jorgenson E, Kaplan R, Kardia SLR, Kelly TN, Kooperberg C, Lasky-Su JA, Loos RJF, Lubitz SA, Mathias RA, McHugh CP, Montgomery C, Moon JY, Morrison AC, Palmer ND, Pankratz N, Papanicolaou GJ, Peralta JM, Peyser PA, Rich SS, Rotter JI, Silverman EK, Smith JA, Smith NL, Taylor KD, Thornton TA, Tiwari HK, Tracy RP, Wang T, Weiss ST, Weng LC, Wiggins KL, Wilson JG, Yanek LR, Zöllner S, North KE, Auer PL; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; TOPMed Hematology & Hemostasis Working Group; Raffield LM, Reiner AP, Li Y. Kowalski MH, et al. Among authors: tiwari hk. PLoS Genet. 2019 Dec 23;15(12):e1008500. doi: 10.1371/journal.pgen.1008500. eCollection 2019 Dec. PLoS Genet. 2019. PMID: 31869403 Free PMC article.
Mixed linear model approach adapted for genome-wide association studies.
Zhang Z, Ersoz E, Lai CQ, Todhunter RJ, Tiwari HK, Gore MA, Bradbury PJ, Yu J, Arnett DK, Ordovas JM, Buckler ES. Zhang Z, et al. Among authors: tiwari hk. Nat Genet. 2010 Apr;42(4):355-60. doi: 10.1038/ng.546. Epub 2010 Mar 7. Nat Genet. 2010. PMID: 20208535 Free PMC article.
Apolipoprotein E polymorphisms and postprandial triglyceridemia before and after fenofibrate treatment in the Genetics of Lipid Lowering and Diet Network (GOLDN) Study.
Irvin MR, Kabagambe EK, Tiwari HK, Parnell LD, Straka RJ, Tsai M, Ordovas JM, Arnett DK. Irvin MR, et al. Among authors: tiwari hk. Circ Cardiovasc Genet. 2010 Oct;3(5):462-7. doi: 10.1161/CIRCGENETICS.110.950667. Epub 2010 Aug 21. Circ Cardiovasc Genet. 2010. PMID: 20729559 Free PMC article.
Imputation of incident events in longitudinal cohort studies.
Howard G, McClure LA, Moy CS, Safford MM, Cushman M, Judd SE, Kissela BM, Kleindorfer DO, Howard VJ, Rhodes DJ, Muntner P, Tiwari HK. Howard G, et al. Among authors: tiwari hk. Am J Epidemiol. 2011 Sep 15;174(6):718-26. doi: 10.1093/aje/kwr155. Epub 2011 Jul 29. Am J Epidemiol. 2011. PMID: 21804050 Free PMC article.
Genes linked to energy metabolism and immunoregulatory mechanisms are associated with subcutaneous adipose tissue distribution in HIV-infected men.
Irvin MR, Shrestha S, Chen YD, Wiener HW, Haritunians T, Vaughan LK, Tiwari HK, Taylor KD, Scherzer R, Saag MS, Grunfeld C, Rotter JI, Arnett DK. Irvin MR, et al. Among authors: tiwari hk. Pharmacogenet Genomics. 2011 Dec;21(12):798-807. doi: 10.1097/FPC.0b013e32834b68f9. Pharmacogenet Genomics. 2011. PMID: 21897333 Free PMC article.
275 results