Toftgard R - Search Results

1

GLI1 regulates a novel neuropilin-2/α6β1 integrin based autocrine pathway that contributes to breast cancer initiation.

Goel HL, Pursell B, Chang C, Shaw LM, Mao J, Simin K, Kumar P, Vander Kooi CW, Shultz LD, Greiner DL, Norum JH, Toftgard R, Kuperwasser C, Mercurio AM. Goel HL, et al. Among authors: toftgard r. EMBO Mol Med. 2013 Apr;5(4):488-508. doi: 10.1002/emmm.201202078. Epub 2013 Feb 21. EMBO Mol Med. 2013. PMID: 23436775 Free PMC article.

2

Regulated splicing of the α6 integrin cytoplasmic domain determines the fate of breast cancer stem cells.

Goel HL, Gritsko T, Pursell B, Chang C, Shultz LD, Greiner DL, Norum JH, Toftgard R, Shaw LM, Mercurio AM. Goel HL, et al. Among authors: toftgard r. Cell Rep. 2014 May 8;7(3):747-61. doi: 10.1016/j.celrep.2014.03.059. Epub 2014 Apr 24. Cell Rep. 2014. PMID: 24767994 Free PMC article.

3

GLI1-induced mammary gland tumours are transplantable and maintain major molecular features.

Norum JH, Frings O, Kasper M, Bergholtz H, Zell Thime H, Bergström Å, Andersson A, Kuiper R, Fredlund E, Sørlie T, Toftgård R. Norum JH, et al. Among authors: toftgard r. Int J Cancer. 2020 Feb 15;146(4):1125-1138. doi: 10.1002/ijc.32522. Epub 2019 Jul 8. Int J Cancer. 2020. PMID: 31219615 Free article.

4

Regulation of Gli1 transcriptional activity in the nucleus by Dyrk1.

Mao J, Maye P, Kogerman P, Tejedor FJ, Toftgard R, Xie W, Wu G, Wu D. Mao J, et al. Among authors: toftgard r. J Biol Chem. 2002 Sep 20;277(38):35156-61. doi: 10.1074/jbc.M206743200. Epub 2002 Jul 22. J Biol Chem. 2002. PMID: 12138125 Free article.

5

A conditional transgenic mouse line for targeted expression of the stem cell marker LGR5.

Norum JH, Bergström Å, Andersson AB, Kuiper RV, Hoelzl MA, Sørlie T, Toftgård R. Norum JH, et al. Among authors: toftgard r. Dev Biol. 2015 Aug 15;404(2):35-48. doi: 10.1016/j.ydbio.2015.05.002. Epub 2015 May 21. Dev Biol. 2015. PMID: 26003047 Free article.

6

β-Catenin-Gli1 interaction regulates proliferation and tumor growth in medulloblastoma.

Zinke J, Schneider FT, Harter PN, Thom S, Ziegler N, Toftgård R, Plate KH, Liebner S. Zinke J, et al. Among authors: toftgard r. Mol Cancer. 2015 Feb 3;14(1):17. doi: 10.1186/s12943-015-0294-4. Mol Cancer. 2015. PMID: 25645196 Free PMC article.

7

SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development.

Raducu M, Fung E, Serres S, Infante P, Barberis A, Fischer R, Bristow C, Thézénas ML, Finta C, Christianson JC, Buffa FM, Kessler BM, Sibson NR, Di Marcotullio L, Toftgård R, D'Angiolella V. Raducu M, et al. Among authors: toftgard r. EMBO J. 2016 Jul 1;35(13):1400-16. doi: 10.15252/embj.201593374. Epub 2016 May 27. EMBO J. 2016. PMID: 27234298 Free PMC article.

8

Development of mammary tumors by conditional expression of GLI1.

Fiaschi M, Rozell B, Bergström A, Toftgård R. Fiaschi M, et al. Among authors: toftgard r. Cancer Res. 2009 Jun 1;69(11):4810-7. doi: 10.1158/0008-5472.CAN-08-3938. Epub 2009 May 19. Cancer Res. 2009. PMID: 19458072 Free PMC article.

9

Hedgehog signalling in breast cancer.

Kasper M, Jaks V, Fiaschi M, Toftgård R. Kasper M, et al. Among authors: toftgard r. Carcinogenesis. 2009 Jun;30(6):903-11. doi: 10.1093/carcin/bgp048. Epub 2009 Feb 23. Carcinogenesis. 2009. PMID: 19237605 Free PMC article. Review.

10

Novel human glioma-associated oncogene 1 (GLI1) splice variants reveal distinct mechanisms in the terminal transduction of the hedgehog signal.

Shimokawa T, Tostar U, Lauth M, Palaniswamy R, Kasper M, Toftgård R, Zaphiropoulos PG. Shimokawa T, et al. Among authors: toftgard r. J Biol Chem. 2008 May 23;283(21):14345-54. doi: 10.1074/jbc.M800299200. Epub 2008 Mar 31. J Biol Chem. 2008. PMID: 18378682 Free PMC article.

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