Tomar T - Search Results

1

Kinome Array Profiling of Patient-Derived Pancreatic Ductal Adenocarcinoma Identifies Differentially Active Protein Tyrosine Kinases.

Creeden JF, Alganem K, Imami AS, Brunicardi FC, Liu SH, Shukla R, Tomar T, Naji F, McCullumsmith RE. Creeden JF, et al. Among authors: tomar t. Int J Mol Sci. 2020 Nov 17;21(22):8679. doi: 10.3390/ijms21228679. Int J Mol Sci. 2020. PMID: 33213062 Free PMC article.

2

Emerging Kinase Therapeutic Targets in Pancreatic Ductal Adenocarcinoma and Pancreatic Cancer Desmoplasia.

Creeden JF, Alganem K, Imami AS, Henkel ND, Brunicardi FC, Liu SH, Shukla R, Tomar T, Naji F, McCullumsmith RE. Creeden JF, et al. Among authors: tomar t. Int J Mol Sci. 2020 Nov 21;21(22):8823. doi: 10.3390/ijms21228823. Int J Mol Sci. 2020. PMID: 33233470 Free PMC article. Review.

3

Identification of Novel Substrates for cGMP Dependent Protein Kinase (PKG) through Kinase Activity Profiling to Understand Its Putative Role in Inherited Retinal Degeneration.

Roy A, Groten J, Marigo V, Tomar T, Hilhorst R. Roy A, et al. Among authors: tomar t. Int J Mol Sci. 2021 Jan 25;22(3):1180. doi: 10.3390/ijms22031180. Int J Mol Sci. 2021. PMID: 33503999 Free PMC article.

4

KRSA: An R package and R Shiny web application for an end-to-end upstream kinase analysis of kinome array data.

DePasquale EAK, Alganem K, Bentea E, Nawreen N, McGuire JL, Tomar T, Naji F, Hilhorst R, Meller J, McCullumsmith RE. DePasquale EAK, et al. Among authors: tomar t. PLoS One. 2021 Dec 17;16(12):e0260440. doi: 10.1371/journal.pone.0260440. eCollection 2021. PLoS One. 2021. PMID: 34919543 Free PMC article.

5

The PKG Inhibitor CN238 Affords Functional Protection of Photoreceptors and Ganglion Cells against Retinal Degeneration.

Tolone A, Haq W, Fachinger A, Roy A, Kesh S, Rentsch A, Wucherpfennig S, Zhu Y, Groten J, Schwede F, Tomar T, Herberg FW, Nache V, Paquet-Durand F. Tolone A, et al. Among authors: tomar t. Int J Mol Sci. 2023 Oct 17;24(20):15277. doi: 10.3390/ijms242015277. Int J Mol Sci. 2023. PMID: 37894958 Free PMC article.

6

Integrative Kinome Profiling Identifies mTORC1/2 Inhibition as Treatment Strategy in Ovarian Clear Cell Carcinoma.

Caumanns JJ, Berns K, Wisman GBA, Fehrmann RSN, Tomar T, Klip H, Meersma GJ, Hijmans EM, Gennissen AMC, Duiker EW, Weening D, Itamochi H, Kluin RJC, Reyners AKL, Birrer MJ, Salvesen HB, Vergote I, van Nieuwenhuysen E, Brenton J, Braicu EI, Kupryjanczyk J, Spiewankiewicz B, Mittempergher L, Bernards R, van der Zee AGJ, de Jong S. Caumanns JJ, et al. Among authors: tomar t. Clin Cancer Res. 2018 Aug 15;24(16):3928-3940. doi: 10.1158/1078-0432.CCR-17-3060. Epub 2018 Apr 23. Clin Cancer Res. 2018. PMID: 29685880 Free PMC article.

7

Combined Inhibition of SHP2 and MEK Is Effective in Models of NF1-Deficient Malignant Peripheral Nerve Sheath Tumors.

Wang J, Pollard K, Allen AN, Tomar T, Pijnenburg D, Yao Z, Rodriguez FJ, Pratilas CA. Wang J, et al. Among authors: tomar t. Cancer Res. 2020 Dec 1;80(23):5367-5379. doi: 10.1158/0008-5472.CAN-20-1365. Epub 2020 Oct 8. Cancer Res. 2020. PMID: 33032988 Free PMC article.

8

Genome-wide methylation profiling of ovarian cancer patient-derived xenografts treated with the demethylating agent decitabine identifies novel epigenetically regulated genes and pathways.

Tomar T, de Jong S, Alkema NG, Hoekman RL, Meersma GJ, Klip HG, van der Zee AG, Wisman GB. Tomar T, et al. Genome Med. 2016 Oct 20;8(1):107. doi: 10.1186/s13073-016-0361-5. Genome Med. 2016. PMID: 27765068 Free PMC article.

9

Kinase activity profiling identifies putative downstream targets of cGMP/PKG signaling in inherited retinal neurodegeneration.

Roy A, Tolone A, Hilhorst R, Groten J, Tomar T, Paquet-Durand F. Roy A, et al. Among authors: tomar t. Cell Death Discov. 2022 Mar 3;8(1):93. doi: 10.1038/s41420-022-00897-7. Cell Death Discov. 2022. PMID: 35241647 Free PMC article.

10

Technological advancements to study cellular signaling pathways in inherited retinal degenerative diseases.

Roy A, Hilhorst R, Groten J, Paquet-Durand F, Tomar T. Roy A, et al. Among authors: tomar t. Curr Opin Pharmacol. 2021 Oct;60:102-110. doi: 10.1016/j.coph.2021.07.002. Epub 2021 Aug 10. Curr Opin Pharmacol. 2021. PMID: 34388439 Review.

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