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Development of reversed-phase high performance liquid chromatography methods for quantification of two isomeric flavones and the application of the methods to pharmacokinetic studies in rats.
Whitted CL, Palau VE, Torrenegra RD, Harirforoosh S. Whitted CL, et al. Among authors: torrenegra rd. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Sep 15;1001:150-5. doi: 10.1016/j.jchromb.2015.07.039. Epub 2015 Jul 26. J Chromatogr B Analyt Technol Biomed Life Sci. 2015. PMID: 26280282
Mechanism of Action of Two Flavone Isomers Targeting Cancer Cells with Varying Cell Differentiation Status.
LeJeune TM, Tsui HY, Parsons LB, Miller GE, Whitted C, Lynch KE, Ramsauer RE, Patel JU, Wyatt JE, Street DS, Adams CB, McPherson B, Tsui HM, Evans JA, Livesay C, Torrenegra RD, Palau VE. LeJeune TM, et al. Among authors: torrenegra rd. PLoS One. 2015 Nov 25;10(11):e0142928. doi: 10.1371/journal.pone.0142928. eCollection 2015. PLoS One. 2015. PMID: 26606169 Free PMC article.
Achyrocline B (3,5 dihydroxy-6,7,8-trimethoxyflavone) synergizes with 5-fluorouracil allowing for dose reduction and reduced off-target toxicity in the treatment of colonic and pancreatic cancers.
Cartwright BM, Corso JN, Lightner J, Whitted C, Torrenegra RD, Krishnan K, Palau VE. Cartwright BM, et al. Among authors: torrenegra rd. Biomed Pharmacother. 2023 Nov;167:115546. doi: 10.1016/j.biopha.2023.115546. Epub 2023 Sep 21. Biomed Pharmacother. 2023. PMID: 37741250 Free article.