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Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro.
Trushina E, Dyer RB, Badger JD 2nd, Ure D, Eide L, Tran DD, Vrieze BT, Legendre-Guillemin V, McPherson PS, Mandavilli BS, Van Houten B, Zeitlin S, McNiven M, Aebersold R, Hayden M, Parisi JE, Seeberg E, Dragatsis I, Doyle K, Bender A, Chacko C, McMurray CT. Trushina E, et al. Among authors: tran dd. Mol Cell Biol. 2004 Sep;24(18):8195-209. doi: 10.1128/MCB.24.18.8195-8209.2004. Mol Cell Biol. 2004. PMID: 15340079 Free PMC article.
CAML loss causes anaphase failure and chromosome missegregation.
Liu Y, Malureanu L, Jeganathan KB, Tran DD, Lindquist LD, van Deursen JM, Bram RJ. Liu Y, et al. Among authors: tran dd. Cell Cycle. 2009 Mar 15;8(6):940-9. doi: 10.4161/cc.8.6.7948. Epub 2009 Mar 26. Cell Cycle. 2009. PMID: 19229138 Free PMC article.
CAML is required for efficient EGF receptor recycling.
Tran DD, Russell HR, Sutor SL, van Deursen J, Bram RJ. Tran DD, et al. Dev Cell. 2003 Aug;5(2):245-56. doi: 10.1016/s1534-5807(03)00207-7. Dev Cell. 2003. PMID: 12919676 Free article.
PIP4K2C inhibition reverses autophagic flux impairment induced by SARS-CoV-2.
Karim M, Mishra M, Lo CW, Saul S, Cagirici HB, Tran DHN, Agrawal A, Ghita L, Ojha A, East MP, Gammeltoft KA, Sahoo MK, Johnson GL, Das S, Jochmans D, Cohen CA, Gottwein J, Dye J, Neff N, Pinsky BA, Laitinen T, Pantsar T, Poso A, Zanini F, Jonghe S, Asquith CRM, Einav S. Karim M, et al. bioRxiv [Preprint]. 2024 Apr 17:2024.04.15.589676. doi: 10.1101/2024.04.15.589676. bioRxiv. 2024. PMID: 38659941 Free PMC article. Preprint.
Back-pocket optimization of 2-aminopyrimidine-based macrocycles leads to potent dual EPHA2/GAK kinase inhibitors with antiviral activity.
Gerninghaus J, Zhubi R, Krämer A, Karim M, Tran DHN, Joerger AC, Schreiber C, Berger LM, Berger BT, Ehret TAL, Elson L, Lenz C, Saxena K, Müller S, Einav S, Knapp S, Hanke T. Gerninghaus J, et al. bioRxiv [Preprint]. 2024 Feb 18:2024.02.18.580805. doi: 10.1101/2024.02.18.580805. bioRxiv. 2024. PMID: 38405908 Free PMC article. Preprint.
332 results