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Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases.
Klarić L, Tsepilov YA, Stanton CM, Mangino M, Sikka TT, Esko T, Pakhomov E, Salo P, Deelen J, McGurnaghan SJ, Keser T, Vučković F, Ugrina I, Krištić J, Gudelj I, Štambuk J, Plomp R, Pučić-Baković M, Pavić T, Vilaj M, Trbojević-Akmačić I, Drake C, Dobrinić P, Mlinarec J, Jelušić B, Richmond A, Timofeeva M, Grishchenko AK, Dmitrieva J, Bermingham ML, Sharapov SZ, Farrington SM, Theodoratou E, Uh HW, Beekman M, Slagboom EP, Louis E, Georges M, Wuhrer M, Colhoun HM, Dunlop MG, Perola M, Fischer K, Polasek O, Campbell H, Rudan I, Wilson JF, Zoldoš V, Vitart V, Spector T, Aulchenko YS, Lauc G, Hayward C. Klarić L, et al. Sci Adv. 2020 Feb 19;6(8):eaax0301. doi: 10.1126/sciadv.aax0301. eCollection 2020 Feb. Sci Adv. 2020. PMID: 32128391 Free PMC article.
Inflammatory bowel disease associates with proinflammatory potential of the immunoglobulin G glycome.
Trbojević Akmačić I, Ventham NT, Theodoratou E, Vučković F, Kennedy NA, Krištić J, Nimmo ER, Kalla R, Drummond H, Štambuk J, Dunlop MG, Novokmet M, Aulchenko Y, Gornik O, Campbell H, Pučić Baković M, Satsangi J, Lauc G; IBD-BIOM Consortium. Trbojević Akmačić I, et al. Inflamm Bowel Dis. 2015 Jun;21(6):1237-47. doi: 10.1097/MIB.0000000000000372. Inflamm Bowel Dis. 2015. PMID: 25895110 Free PMC article.
Association of systemic lupus erythematosus with decreased immunosuppressive potential of the IgG glycome.
Vučković F, Krištić J, Gudelj I, Teruel M, Keser T, Pezer M, Pučić-Baković M, Štambuk J, Trbojević-Akmačić I, Barrios C, Pavić T, Menni C, Wang Y, Zhou Y, Cui L, Song H, Zeng Q, Guo X, Pons-Estel BA, McKeigue P, Leslie Patrick A, Gornik O, Spector TD, Harjaček M, Alarcon-Riquelme M, Molokhia M, Wang W, Lauc G. Vučković F, et al. Arthritis Rheumatol. 2015 Nov;67(11):2978-89. doi: 10.1002/art.39273. Arthritis Rheumatol. 2015. PMID: 26200652 Free PMC article.
IgG and IgM glycosylation patterns in patients undergoing image-guided tumor ablation.
Breen LD, Pučić-Baković M, Vučković F, Reiding K, Trbojević-Akmačić I, Šrajer Gajdošik M, Cook MI, Lopez MJ, Wuhrer M, Camara LM, Andjelković U, Dupuy DE, Josić D. Breen LD, et al. Biochim Biophys Acta. 2016 Aug;1860(8):1786-94. doi: 10.1016/j.bbagen.2016.01.011. Epub 2016 Jan 29. Biochim Biophys Acta. 2016. PMID: 26827872
High-throughput analysis of immunoglobulin G glycosylation.
Trbojević-Akmačić I, Vilaj M, Lauc G. Trbojević-Akmačić I, et al. Expert Rev Proteomics. 2016 May;13(5):523-34. doi: 10.1080/14789450.2016.1174584. Epub 2016 Apr 22. Expert Rev Proteomics. 2016. PMID: 27043342 Review.
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