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Page 1
Harmonizing Genetic Ancestry and Self-identified Race/Ethnicity in Genome-wide Association Studies.
Fang H, Hui Q, Lynch J, Honerlaw J, Assimes TL, Huang J, Vujkovic M, Damrauer SM, Pyarajan S, Gaziano JM, DuVall SL, O'Donnell CJ, Cho K, Chang KM, Wilson PWF, Tsao PS; VA Million Veteran Program; Sun YV, Tang H. Fang H, et al. Among authors: tsao ps. Am J Hum Genet. 2019 Oct 3;105(4):763-772. doi: 10.1016/j.ajhg.2019.08.012. Epub 2019 Sep 26. Am J Hum Genet. 2019. PMID: 31564439 Free PMC article.
A Multi-Ancestry Polygenic Risk Score for Coronary Heart Disease Based on an Ancestrally Diverse Genome-Wide Association Study and Population-Specific Optimization.
Smith JL, Tcheandjieu C, Dikilitas O, Lyer K, Miyazawa K, Hilliard A, Lynch J, Rotter JI, Chen YI, Sheu WH, Chang KM, Kanoni S, Tsao P, Ito K, Kosel M, Clarke SL, Schaid DJ, Assimes TL, Kullo IJ. Smith JL, et al. medRxiv [Preprint]. 2023 Jun 6:2023.06.02.23290896. doi: 10.1101/2023.06.02.23290896. medRxiv. 2023. PMID: 37609230 Free PMC article. Updated. Preprint.
Profiling the genome and proteome of metabolic dysfunction-associated steatotic liver disease identifies potential therapeutic targets.
Liu J, Hu S, Chen L, Daly C, Prada Medina CA, Richardson TG, Traylor M, Dempster NJ, Mbasu R, Monfeuga T, Vujkovic M, Tsao PS, Lynch JA, Voight BF, Chang KM, Million VA, Cobbold JF, Tomlinson JW, van Duijn CM, Howson JMM. Liu J, et al. Among authors: tsao ps. medRxiv [Preprint]. 2023 Nov 30:2023.11.30.23299247. doi: 10.1101/2023.11.30.23299247. medRxiv. 2023. PMID: 38076879 Free PMC article. Preprint.
Admixture Mapping of Peripheral Artery Disease in a Dominican Population Reveals a Novel Risk Locus on 2q35.
Cullina S, Wojcik GL, Shemirani R, Klarin D, Gorman BR, Sorokin EP, Gignoux CR, Belbin GM, Pyarajan S, Asgari S, Tsao PS, Damrauer SM, Abul-Husn NS, Kenny EE. Cullina S, et al. Among authors: tsao ps. medRxiv [Preprint]. 2023 Mar 29:2023.03.27.23287788. doi: 10.1101/2023.03.27.23287788. medRxiv. 2023. PMID: 37034679 Free PMC article. Updated. Preprint.
Common and rare variant analyses combined with single-cell multiomics reveal cell-type-specific molecular mechanisms of COVID-19 severity.
Zhang S, Cooper-Knock J, Weimer AK, Harvey C, Julian TH, Wang C, Li J, Furini S, Frullanti E, Fava F, Renieri A, Pan C, Song J, Billing-Ross P, Gao P, Shen X, Timpanaro IS, Kenna KP; VA Million Veteran Program; GEN-COVID Network; Davis MM, Tsao PS, Snyder MP. Zhang S, et al. Among authors: tsao ps. medRxiv [Preprint]. 2021 Jun 21:2021.06.15.21258703. doi: 10.1101/2021.06.15.21258703. medRxiv. 2021. PMID: 34189540 Free PMC article. Updated. Preprint.
Deep learning modeling of rare noncoding genetic variants in human motor neurons defines CCDC146 as a therapeutic target for ALS.
Zhang S, Moll T, Rubin-Sigler J, Tu S, Li S, Yuan E, Liu M, Butt A, Harvey C, Gornall S, Alhalthli E, Shaw A, Souza CDS, Ferraiuolo L, Hornstein E, Shelkovnikova T, van Dijk CH, Timpanaro IS, Kenna KP, Zeng J, Tsao PS, Shaw PJ, Ichida JK, Cooper-Knock J, Snyder MP. Zhang S, et al. Among authors: tsao ps. medRxiv [Preprint]. 2024 Apr 1:2024.03.30.24305115. doi: 10.1101/2024.03.30.24305115. medRxiv. 2024. PMID: 38633814 Free PMC article. Preprint.
Integrative common and rare variant analyses provide insights into the genetic architecture of liver cirrhosis.
Ghouse J, Sveinbjörnsson G, Vujkovic M, Seidelin AS, Gellert-Kristensen H, Ahlberg G, Tragante V, Rand SA, Brancale J, Vilarinho S, Lundegaard PR, Sørensen E, Erikstrup C, Bruun MT, Jensen BA, Brunak S, Banasik K, Ullum H; DBDS Genomic Consortium; Verweij N, Lotta L, Baras A; Regeneron Genetics Center; Mirshahi T, Carey DJ; Geisinger-Regeneron DiscovEHR Collaboration; VA Million Veteran Program; Kaplan DE, Lynch J, Morgan T, Schwantes-An TH, Dochtermann DR, Pyarajan S, Tsao PS; Estonian Biobank Research Team; Laisk T, Mägi R, Kozlitina J, Tybjærg-Hansen A, Jones D, Knowlton KU, Nadauld L, Ferkingstad E, Björnsson ES, Ulfarsson MO, Sturluson Á, Sulem P, Pedersen OB, Ostrowski SR, Gudbjartsson DF, Stefansson K, Olesen MS, Chang KM, Holm H, Bundgaard H, Stender S. Ghouse J, et al. Among authors: tsao ps. Nat Genet. 2024 Apr 17. doi: 10.1038/s41588-024-01720-y. Online ahead of print. Nat Genet. 2024. PMID: 38632349
Type 1 Diabetes Genetic Risk in 109,954 Veterans With Adult-Onset Diabetes: The Million Veteran Program (MVP).
Yang PK, Jackson SL, Charest BR, Cheng YJ, Sun YV, Raghavan S, Litkowski EM, Legvold BT, Rhee MK, Oram RA, Kuklina EV, Vujkovic M, Reaven PD, Cho K, Leong A, Wilson PWF, Zhou J, Miller DR, Sharp SA, Staimez LR, North KE, Highland HM, Phillips LS; Million Veteran Program. Yang PK, et al. Diabetes Care. 2024 Apr 12:dc231927. doi: 10.2337/dc23-1927. Online ahead of print. Diabetes Care. 2024. PMID: 38608262
332 results