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The nucleotide excision repair protein XPC is essential for bulky DNA adducts to promote interleukin-6 expression via the activation of p38-SAPK.
Schreck I, Grico N, Hansjosten I, Marquardt C, Bormann S, Seidel A, Kvietkova DL, Pieniazek D, Segerbäck D, Diabaté S, van der Horst GT, Oesch-Bartlomowicz B, Oesch F, Weiss C. Schreck I, et al. Among authors: van der horst gt. Oncogene. 2016 Feb 18;35(7):908-18. doi: 10.1038/onc.2015.145. Epub 2015 May 18. Oncogene. 2016. PMID: 25982271
Proteins of nucleotide and base excision repair pathways interact in mitochondria to protect from loss of subcutaneous fat, a hallmark of aging.
Kamenisch Y, Fousteri M, Knoch J, von Thaler AK, Fehrenbacher B, Kato H, Becker T, Dollé ME, Kuiper R, Majora M, Schaller M, van der Horst GT, van Steeg H, Röcken M, Rapaport D, Krutmann J, Mullenders LH, Berneburg M. Kamenisch Y, et al. Among authors: van der horst gt, van steeg h. J Exp Med. 2010 Feb 15;207(2):379-90. doi: 10.1084/jem.20091834. Epub 2010 Jan 25. J Exp Med. 2010. PMID: 20100872 Free PMC article.
Different effects of CSA and CSB deficiency on sensitivity to oxidative DNA damage.
de Waard H, de Wit J, Andressoo JO, van Oostrom CT, Riis B, Weimann A, Poulsen HE, van Steeg H, Hoeijmakers JH, van der Horst GT. de Waard H, et al. Among authors: van der horst gt, van steeg h, van oostrom ct. Mol Cell Biol. 2004 Sep;24(18):7941-8. doi: 10.1128/MCB.24.18.7941-7948.2004. Mol Cell Biol. 2004. PMID: 15340056 Free PMC article.
Early postnatal ataxia and abnormal cerebellar development in mice lacking Xeroderma pigmentosum Group A and Cockayne syndrome Group B DNA repair genes.
Murai M, Enokido Y, Inamura N, Yoshino M, Nakatsu Y, van der Horst GT, Hoeijmakers JH, Tanaka K, Hatanaka H. Murai M, et al. Among authors: van der horst gt. Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):13379-84. doi: 10.1073/pnas.231329598. Epub 2001 Oct 30. Proc Natl Acad Sci U S A. 2001. PMID: 11687625 Free PMC article.
173 results