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Page 1
A small molecule alpha4beta1/alpha4beta7 antagonist differentiates between the low-affinity states of alpha4beta1 and alpha4beta7: characterization of divalent cation dependence.
Egger LA, Cao J, McCallum C, Kidambi U, Van Riper G, McCauley E, Mumford RA, Lanza TJ, Lin LS, de Laszlo SE, Young DN, Yang G, Dean DC, Raab CE, Wallace MA, Jones AN, Hagmann WK, Schmidt JA, Pepinsky RB, Scott DM, Lee WC, Cornebise MA, Detmers PA. Egger LA, et al. Among authors: van riper g. J Pharmacol Exp Ther. 2003 Sep;306(3):903-13. doi: 10.1124/jpet.102.047704. Epub 2003 May 23. J Pharmacol Exp Ther. 2003. PMID: 12766251
Specific and dual antagonists of alpha(4)beta(1) and alpha(4)beta(7) integrins.
Lin LS, Lanza T Jr, McCauley E, Van Riper G, Kidambi U, Cao J, Egger LA, Mumford RA, Schmidt JA, MacCoss M, Hagmann WK. Lin LS, et al. Among authors: van riper g. Bioorg Med Chem Lett. 2002 Jan 21;12(2):133-6. doi: 10.1016/s0960-894x(01)00705-3. Bioorg Med Chem Lett. 2002. PMID: 11755338
Alpha(4)beta(7)/alpha(4)beta(1) dual integrin antagonists block alpha(4)beta(7)-dependent adhesion under shear flow.
Egger LA, Kidambi U, Cao J, Van Riper G, McCauley E, Mumford RA, Amo S, Lingham R, Lanza T, Lin LS, De Laszlo SE, Young DN, Kopka IE, Tong S, Pikounis B, Benson E, Warwood S, Bargatze RF, Hagmann WK, Schmidt JA, Detmers PA. Egger LA, et al. Among authors: van riper g. J Pharmacol Exp Ther. 2002 Jul;302(1):153-62. doi: 10.1124/jpet.302.1.153. J Pharmacol Exp Ther. 2002. PMID: 12065712
Effects of VLA-4 antagonists in rat whole embryo culture.
Spence S, Vetter C, Hagmann WK, Van Riper G, Williams H, Mumford RA, Lanza TJ, Lin LS, Schmidt JA. Spence S, et al. Among authors: van riper g. Teratology. 2002 Jan;65(1):26-37. doi: 10.1002/tera.1095. Teratology. 2002. PMID: 11835229
Substituted N-(3,5-dichlorobenzenesulfonyl)-L-prolyl-phenylalanine analogues as potent VLA-4 antagonists.
Kopka IE, Young DN, Lin LS, Mumford RA, Magriotis PA, MacCoss M, Mills SG, Van Riper G, McCauley E, Egger LE, Kidambi U, Schmidt JA, Lyons K, Stearns R, Vincent S, Colletti A, Wang Z, Tong S, Wang J, Zheng S, Owens K, Levorse D, Hagmann WK. Kopka IE, et al. Among authors: van riper g. Bioorg Med Chem Lett. 2002 Feb 25;12(4):637-40. doi: 10.1016/s0960-894x(01)00821-6. Bioorg Med Chem Lett. 2002. PMID: 11844689
N-aryl 2,6-dimethoxybiphenylalanine analogues as VLA-4 antagonists.
Doherty GA, Kamenecka T, McCauley E, Van Riper G, Mumford RA, Tong S, Hagmann WK. Doherty GA, et al. Among authors: van riper g. Bioorg Med Chem Lett. 2002 Mar 11;12(5):729-31. doi: 10.1016/s0960-894x(02)00009-4. Bioorg Med Chem Lett. 2002. PMID: 11858990
N-Tetrahydrofuroyl-(L)-phenylalanine derivatives as potent VLA-4 antagonists.
Yang GX, Chang LL, Truong Q, Doherty GA, Magriotis PA, de Laszlo SE, Li B, MacCoss M, Kidambi U, Egger LA, McCauley E, Van Riper G, Mumford RA, Schmidt JA, Hagmann WK. Yang GX, et al. Among authors: van riper g. Bioorg Med Chem Lett. 2002 Jun 3;12(11):1497-500. doi: 10.1016/s0960-894x(02)00210-x. Bioorg Med Chem Lett. 2002. PMID: 12031328
30 results