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A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation.
Coviello AD, Haring R, Wellons M, Vaidya D, Lehtimäki T, Keildson S, Lunetta KL, He C, Fornage M, Lagou V, Mangino M, Onland-Moret NC, Chen B, Eriksson J, Garcia M, Liu YM, Koster A, Lohman K, Lyytikäinen LP, Petersen AK, Prescott J, Stolk L, Vandenput L, Wood AR, Zhuang WV, Ruokonen A, Hartikainen AL, Pouta A, Bandinelli S, Biffar R, Brabant G, Cox DG, Chen Y, Cummings S, Ferrucci L, Gunter MJ, Hankinson SE, Martikainen H, Hofman A, Homuth G, Illig T, Jansson JO, Johnson AD, Karasik D, Karlsson M, Kettunen J, Kiel DP, Kraft P, Liu J, Ljunggren Ö, Lorentzon M, Maggio M, Markus MR, Mellström D, Miljkovic I, Mirel D, Nelson S, Morin Papunen L, Peeters PH, Prokopenko I, Raffel L, Reincke M, Reiner AP, Rexrode K, Rivadeneira F, Schwartz SM, Siscovick D, Soranzo N, Stöckl D, Tworoger S, Uitterlinden AG, van Gils CH, Vasan RS, Wichmann HE, Zhai G, Bhasin S, Bidlingmaier M, Chanock SJ, De Vivo I, Harris TB, Hunter DJ, Kähönen M, Liu S, Ouyang P, Spector TD, van der Schouw YT, Viikari J, Wallaschofski H, McCarthy MI, Frayling TM, Murray A, Franks S, Järvelin MR, de Jong FH, Raitakari O, Teumer A, Ohlsson C, Murabito JM, Perry JR. Coviello AD, et al. Among authors: vandenput l. PLoS Genet. 2012;8(7):e1002805. doi: 10.1371/journal.pgen.1002805. Epub 2012 Jul 19. PLoS Genet. 2012. PMID: 22829776 Free PMC article.
SHBG gene promoter polymorphisms in men are associated with serum sex hormone-binding globulin, androgen and androgen metabolite levels, and hip bone mineral density.
Eriksson AL, Lorentzon M, Mellström D, Vandenput L, Swanson C, Andersson N, Hammond GL, Jakobsson J, Rane A, Orwoll ES, Ljunggren O, Johnell O, Labrie F, Windahl SH, Ohlsson C. Eriksson AL, et al. Among authors: vandenput l. J Clin Endocrinol Metab. 2006 Dec;91(12):5029-37. doi: 10.1210/jc.2006-0679. Epub 2006 Aug 22. J Clin Endocrinol Metab. 2006. PMID: 16926255
The uridine diphosphate glucuronosyltransferase 2B15 D85Y and 2B17 deletion polymorphisms predict the glucuronidation pattern of androgens and fat mass in men.
Swanson C, Mellström D, Lorentzon M, Vandenput L, Jakobsson J, Rane A, Karlsson M, Ljunggren O, Smith U, Eriksson AL, Bélanger A, Labrie F, Ohlsson C. Swanson C, et al. Among authors: vandenput l. J Clin Endocrinol Metab. 2007 Dec;92(12):4878-82. doi: 10.1210/jc.2007-0359. Epub 2007 Aug 14. J Clin Endocrinol Metab. 2007. PMID: 17698910
Comparable amounts of sex steroids are made outside the gonads in men and women: strong lesson for hormone therapy of prostate and breast cancer.
Labrie F, Cusan L, Gomez JL, Martel C, Bérubé R, Bélanger P, Bélanger A, Vandenput L, Mellström D, Ohlsson C. Labrie F, et al. Among authors: vandenput l. J Steroid Biochem Mol Biol. 2009 Jan;113(1-2):52-6. doi: 10.1016/j.jsbmb.2008.11.004. Epub 2008 Nov 27. J Steroid Biochem Mol Biol. 2009. PMID: 19073258
Genetic variations in sex steroid-related genes as predictors of serum estrogen levels in men.
Eriksson AL, Lorentzon M, Vandenput L, Labrie F, Lindersson M, Syvänen AC, Orwoll ES, Cummings SR, Zmuda JM, Ljunggren O, Karlsson MK, Mellström D, Ohlsson C. Eriksson AL, et al. Among authors: vandenput l. J Clin Endocrinol Metab. 2009 Mar;94(3):1033-41. doi: 10.1210/jc.2008-1283. Epub 2008 Dec 30. J Clin Endocrinol Metab. 2009. PMID: 19116238 Free PMC article.
The role of estrogens for male bone health.
Ohlsson C, Vandenput L. Ohlsson C, et al. Among authors: vandenput l. Eur J Endocrinol. 2009 Jun;160(6):883-9. doi: 10.1530/EJE-09-0118. Epub 2009 Mar 20. Eur J Endocrinol. 2009. PMID: 19304870 Review.
161 results