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Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.
Ligthart S, Vaez A, Võsa U, Stathopoulou MG, de Vries PS, Prins BP, Van der Most PJ, Tanaka T, Naderi E, Rose LM, Wu Y, Karlsson R, Barbalic M, Lin H, Pool R, Zhu G, Macé A, Sidore C, Trompet S, Mangino M, Sabater-Lleal M, Kemp JP, Abbasi A, Kacprowski T, Verweij N, Smith AV, Huang T, Marzi C, Feitosa MF, Lohman KK, Kleber ME, Milaneschi Y, Mueller C, Huq M, Vlachopoulou E, Lyytikäinen LP, Oldmeadow C, Deelen J, Perola M, Zhao JH, Feenstra B; LifeLines Cohort Study; Amini M; CHARGE Inflammation Working Group; Lahti J, Schraut KE, Fornage M, Suktitipat B, Chen WM, Li X, Nutile T, Malerba G, Luan J, Bak T, Schork N, Del Greco M F, Thiering E, Mahajan A, Marioni RE, Mihailov E, Eriksson J, Ozel AB, Zhang W, Nethander M, Cheng YC, Aslibekyan S, Ang W, Gandin I, Yengo L, Portas L, Kooperberg C, Hofer E, Rajan KB, Schurmann C, den Hollander W, Ahluwalia TS, Zhao J, Draisma HHM, Ford I, Timpson N, Teumer A, Huang H, Wahl S, Liu Y, Huang J, Uh HW, Geller F, Joshi PK, Yanek LR, Trabetti E, Lehne B, Vozzi D, Verbanck M, Biino G, Saba Y, Meulenbelt I, O'Connell JR, Laakso M, Giulianini F, Magnusson PKE, Ballantyne CM, Hottenga JJ, Montgomery GW, Rivadineira F, Rueedi R, Steri M, Herzig KH, S… See abstract for full author list ➔ Ligthart S, et al. Among authors: vandenput l. Am J Hum Genet. 2018 Nov 1;103(5):691-706. doi: 10.1016/j.ajhg.2018.09.009. Am J Hum Genet. 2018. PMID: 30388399 Free PMC article.
SHBG gene promoter polymorphisms in men are associated with serum sex hormone-binding globulin, androgen and androgen metabolite levels, and hip bone mineral density.
Eriksson AL, Lorentzon M, Mellström D, Vandenput L, Swanson C, Andersson N, Hammond GL, Jakobsson J, Rane A, Orwoll ES, Ljunggren O, Johnell O, Labrie F, Windahl SH, Ohlsson C. Eriksson AL, et al. Among authors: vandenput l. J Clin Endocrinol Metab. 2006 Dec;91(12):5029-37. doi: 10.1210/jc.2006-0679. Epub 2006 Aug 22. J Clin Endocrinol Metab. 2006. PMID: 16926255
The uridine diphosphate glucuronosyltransferase 2B15 D85Y and 2B17 deletion polymorphisms predict the glucuronidation pattern of androgens and fat mass in men.
Swanson C, Mellström D, Lorentzon M, Vandenput L, Jakobsson J, Rane A, Karlsson M, Ljunggren O, Smith U, Eriksson AL, Bélanger A, Labrie F, Ohlsson C. Swanson C, et al. Among authors: vandenput l. J Clin Endocrinol Metab. 2007 Dec;92(12):4878-82. doi: 10.1210/jc.2007-0359. Epub 2007 Aug 14. J Clin Endocrinol Metab. 2007. PMID: 17698910
Genetic variations in sex steroid-related genes as predictors of serum estrogen levels in men.
Eriksson AL, Lorentzon M, Vandenput L, Labrie F, Lindersson M, Syvänen AC, Orwoll ES, Cummings SR, Zmuda JM, Ljunggren O, Karlsson MK, Mellström D, Ohlsson C. Eriksson AL, et al. Among authors: vandenput l. J Clin Endocrinol Metab. 2009 Mar;94(3):1033-41. doi: 10.1210/jc.2008-1283. Epub 2008 Dec 30. J Clin Endocrinol Metab. 2009. PMID: 19116238 Free PMC article.
The role of estrogens for male bone health.
Ohlsson C, Vandenput L. Ohlsson C, et al. Among authors: vandenput l. Eur J Endocrinol. 2009 Jun;160(6):883-9. doi: 10.1530/EJE-09-0118. Epub 2009 Mar 20. Eur J Endocrinol. 2009. PMID: 19304870 Review.
Low serum testosterone and estradiol predict mortality in elderly men.
Tivesten A, Vandenput L, Labrie F, Karlsson MK, Ljunggren O, Mellström D, Ohlsson C. Tivesten A, et al. Among authors: vandenput l. J Clin Endocrinol Metab. 2009 Jul;94(7):2482-8. doi: 10.1210/jc.2008-2650. Epub 2009 Apr 28. J Clin Endocrinol Metab. 2009. PMID: 19401373
161 results