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A Trimeric HIV-1 Envelope gp120 Immunogen Induces Potent and Broad Anti-V1V2 Loop Antibodies against HIV-1 in Rabbits and Rhesus Macaques.
Jones AT, Chamcha V, Kesavardhana S, Shen X, Beaumont D, Das R, Wyatt LS, LaBranche CC, Stanfield-Oakley S, Ferrari G, Montefiori DC, Moss B, Tomaras GD, Varadarajan R, Amara RR. Jones AT, et al. Among authors: varadarajan r. J Virol. 2018 Feb 12;92(5):e01796-17. doi: 10.1128/JVI.01796-17. Print 2018 Mar 1. J Virol. 2018. PMID: 29237847 Free PMC article.
Characterization of gp120 and its single-chain derivatives, gp120-CD4D12 and gp120-M9: implications for targeting the CD4i epitope in human immunodeficiency virus vaccine design.
Varadarajan R, Sharma D, Chakraborty K, Patel M, Citron M, Sinha P, Yadav R, Rashid U, Kennedy S, Eckert D, Geleziunas R, Bramhill D, Schleif W, Liang X, Shiver J. Varadarajan R, et al. J Virol. 2005 Feb;79(3):1713-23. doi: 10.1128/JVI.79.3.1713-1723.2005. J Virol. 2005. PMID: 15650196 Free PMC article.
Design of an Escherichia coli expressed HIV-1 gp120 fragment immunogen that binds to b12 and induces broad and potent neutralizing antibodies.
Bhattacharyya S, Singh P, Rathore U, Purwar M, Wagner D, Arendt H, DeStefano J, LaBranche CC, Montefiori DC, Phogat S, Varadarajan R. Bhattacharyya S, et al. Among authors: varadarajan r. J Biol Chem. 2013 Apr 5;288(14):9815-9825. doi: 10.1074/jbc.M112.425959. Epub 2013 Feb 21. J Biol Chem. 2013. PMID: 23430741 Free PMC article.
Immunogen design for HIV-1 and influenza.
Rathore U, Kesavardhana S, Mallajosyula VV, Varadarajan R. Rathore U, et al. Among authors: varadarajan r. Biochim Biophys Acta. 2014 Nov;1844(11):1891-1906. doi: 10.1016/j.bbapap.2014.05.010. Epub 2014 Jun 2. Biochim Biophys Acta. 2014. PMID: 24892211 Review.
209 results