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Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.
Wain LV, Shrine N, Artigas MS, Erzurumluoglu AM, Noyvert B, Bossini-Castillo L, Obeidat M, Henry AP, Portelli MA, Hall RJ, Billington CK, Rimington TL, Fenech AG, John C, Blake T, Jackson VE, Allen RJ, Prins BP; Understanding Society Scientific Group; Campbell A, Porteous DJ, Jarvelin MR, Wielscher M, James AL, Hui J, Wareham NJ, Zhao JH, Wilson JF, Joshi PK, Stubbe B, Rawal R, Schulz H, Imboden M, Probst-Hensch NM, Karrasch S, Gieger C, Deary IJ, Harris SE, Marten J, Rudan I, Enroth S, Gyllensten U, Kerr SM, Polasek O, Kähönen M, Surakka I, Vitart V, Hayward C, Lehtimäki T, Raitakari OT, Evans DM, Henderson AJ, Pennell CE, Wang CA, Sly PD, Wan ES, Busch R, Hobbs BD, Litonjua AA, Sparrow DW, Gulsvik A, Bakke PS, Crapo JD, Beaty TH, Hansel NN, Mathias RA, Ruczinski I, Barnes KC, Bossé Y, Joubert P, van den Berge M, Brandsma CA, Paré PD, Sin DD, Nickle DC, Hao K, Gottesman O, Dewey FE, Bruse SE, Carey DJ, Kirchner HL; Geisinger-Regeneron DiscovEHR Collaboration; Jonsson S, Thorleifsson G, Jonsdottir I, Gislason T, Stefansson K, Schurmann C, Nadkarni G, Bottinger EP, Loos RJ, Walters RG, Chen Z, Millwood IY, Vaucher J, Kurmi OP, Li L, Hansell AL, Brightling C, Zeggini E, Cho M… See abstract for full author list ➔ Wain LV, et al. Among authors: vaucher j. Nat Genet. 2017 Mar;49(3):416-425. doi: 10.1038/ng.3787. Epub 2017 Feb 6. Nat Genet. 2017. PMID: 28166213 Free PMC article.
Validity of COPD diagnoses reported through nationwide health insurance systems in the People's Republic of China.
Kurmi OP, Vaucher J, Xiao D, Holmes MV, Guo Y, Davis KJ, Wang C, Qin H, Turnbull I, Peng P, Bian Z, Clarke R, Li L, Chen Y, Chen Z. Kurmi OP, et al. Among authors: vaucher j. Int J Chron Obstruct Pulmon Dis. 2016 Mar 1;11:419-30. doi: 10.2147/COPD.S100736. eCollection 2016. Int J Chron Obstruct Pulmon Dis. 2016. PMID: 27042034 Free PMC article.
Genetic variants associated with type 2 diabetes and adiposity and risk of intracranial and abdominal aortic aneurysms.
van 't Hof FN, Vaucher J, Holmes MV, de Wilde A, Baas AF, Blankensteijn JD, Hofman A, Kiemeney LA, Rivadeneira F, Uitterlinden AG, Vermeulen SH, Rinkel GJ, de Bakker PI, Ruigrok YM. van 't Hof FN, et al. Among authors: vaucher j. Eur J Hum Genet. 2017 Jun;25(6):758-762. doi: 10.1038/ejhg.2017.48. Epub 2017 Apr 5. Eur J Hum Genet. 2017. PMID: 28378816 Free PMC article.
Patterns and management of chronic obstructive pulmonary disease in urban and rural China: a community-based survey of 25 000 adults across 10 regions.
Kurmi OP, Davis KJ, Hubert Lam KB, Guo Y, Vaucher J, Bennett D, Wang J, Bian Z, Du H, Li L, Clarke R, Chen Z. Kurmi OP, et al. Among authors: vaucher j. BMJ Open Respir Res. 2018 Feb 19;5(1):e000267. doi: 10.1136/bmjresp-2017-000267. eCollection 2018. BMJ Open Respir Res. 2018. PMID: 29531747 Free PMC article.
Genetic Predisposition to Type 2 Diabetes and Risk of Subclinical Atherosclerosis and Cardiovascular Diseases Among 160,000 Chinese Adults.
Gan W, Bragg F, Walters RG, Millwood IY, Lin K, Chen Y, Guo Y, Vaucher J, Bian Z, Bennett D, Lv J, Yu C, Mahajan A, Clarke RJ, Li L, Holmes MV, McCarthy MI, Chen Z; China Kadoorie Biobank Collaborative Group. Gan W, et al. Among authors: vaucher j. Diabetes. 2019 Nov;68(11):2155-2164. doi: 10.2337/db19-0224. Epub 2019 Aug 9. Diabetes. 2019. PMID: 31399431 Free PMC article.
Cannabis use and risk of schizophrenia: a Mendelian randomization study.
Vaucher J, Keating BJ, Lasserre AM, Gan W, Lyall DM, Ward J, Smith DJ, Pell JP, Sattar N, Paré G, Holmes MV. Vaucher J, et al. Mol Psychiatry. 2018 May;23(5):1287-1292. doi: 10.1038/mp.2016.252. Epub 2017 Jan 24. Mol Psychiatry. 2018. PMID: 28115737 Free PMC article.
Education and coronary heart disease: mendelian randomisation study.
Tillmann T, Vaucher J, Okbay A, Pikhart H, Peasey A, Kubinova R, Pajak A, Tamosiunas A, Malyutina S, Hartwig FP, Fischer K, Veronesi G, Palmer T, Bowden J, Davey Smith G, Bobak M, Holmes MV. Tillmann T, et al. Among authors: vaucher j. BMJ. 2017 Aug 30;358:j3542. doi: 10.1136/bmj.j3542. BMJ. 2017. PMID: 28855160 Free PMC article.
94 results