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Mre11 exonuclease activity removes the chain-terminating nucleoside analog gemcitabine from the nascent strand during DNA replication.
Boeckemeier L, Kraehenbuehl R, Keszthelyi A, Gasasira MU, Vernon EG, Beardmore R, Vågbø CB, Chaplin D, Gollins S, Krokan HE, Lambert SAE, Paizs B, Hartsuiker E. Boeckemeier L, et al. Among authors: vernon eg. Sci Adv. 2020 May 29;6(22):eaaz4126. doi: 10.1126/sciadv.aaz4126. eCollection 2020 May. Sci Adv. 2020. PMID: 32523988 Free PMC article.
MRNIP is a replication fork protection factor.
Bennett LG, Wilkie AM, Antonopoulou E, Ceppi I, Sanchez A, Vernon EG, Gamble A, Myers KN, Collis SJ, Cejka P, Staples CJ. Bennett LG, et al. Among authors: vernon eg. Sci Adv. 2020 Jul 10;6(28):eaba5974. doi: 10.1126/sciadv.aba5974. eCollection 2020 Jul. Sci Adv. 2020. PMID: 32832601 Free PMC article.
Insulin-like growth factor binding protein 3 has opposing actions on malignant and nonmalignant breast epithelial cells that are each reversible and dependent upon cholesterol-stabilized integrin receptor complexes.
Burrows C, Holly JM, Laurence NJ, Vernon EG, Carter JV, Clark MA, McIntosh J, McCaig C, Winters ZE, Perks CM. Burrows C, et al. Among authors: vernon eg. Endocrinology. 2006 Jul;147(7):3484-500. doi: 10.1210/en.2006-0005. Epub 2006 Apr 13. Endocrinology. 2006. PMID: 16614079
CDK4/6 inhibitor-mediated cell overgrowth triggers osmotic and replication stress to promote senescence.
Crozier L, Foy R, Adib R, Kar A, Holt JA, Pareri AU, Valverde JM, Rivera R, Weston WA, Wilson R, Regnault C, Whitfield P, Badonyi M, Bennett LG, Vernon EG, Gamble A, Marsh JA, Staples CJ, Saurin AT, Barr AR, Ly T. Crozier L, et al. Among authors: vernon eg. Mol Cell. 2023 Nov 16;83(22):4062-4077.e5. doi: 10.1016/j.molcel.2023.10.016. Epub 2023 Nov 16. Mol Cell. 2023. PMID: 37977118 Free article.
11 results