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The androgen receptor controls expression of the cancer-associated sTn antigen and cell adhesion through induction of ST6GalNAc1 in prostate cancer.
Munkley J, Oltean S, Vodák D, Wilson BT, Livermore KE, Zhou Y, Star E, Floros VI, Johannessen B, Knight B, McCullagh P, McGrath J, Crundwell M, Skotheim RI, Robson CN, Leung HY, Harries LW, Rajan P, Mills IG, Elliott DJ. Munkley J, et al. Oncotarget. 2015 Oct 27;6(33):34358-74. doi: 10.18632/oncotarget.6024. Oncotarget. 2015. PMID: 26452038 Free PMC article.
Human Tra2 proteins jointly control a CHEK1 splicing switch among alternative and constitutive target exons.
Best A, James K, Dalgliesh C, Hong E, Kheirolahi-Kouhestani M, Curk T, Xu Y, Danilenko M, Hussain R, Keavney B, Wipat A, Klinck R, Cowell IG, Cheong Lee K, Austin CA, Venables JP, Chabot B, Santibanez Koref M, Tyson-Capper A, Elliott DJ. Best A, et al. Nat Commun. 2014 Sep 11;5:4760. doi: 10.1038/ncomms5760. Nat Commun. 2014. PMID: 25208576 Free PMC article.
The splicing landscape is globally reprogrammed during male meiosis.
Schmid R, Grellscheid SN, Ehrmann I, Dalgliesh C, Danilenko M, Paronetto MP, Pedrotti S, Grellscheid D, Dixon RJ, Sette C, Eperon IC, Elliott DJ. Schmid R, et al. Nucleic Acids Res. 2013 Dec;41(22):10170-84. doi: 10.1093/nar/gkt811. Epub 2013 Sep 12. Nucleic Acids Res. 2013. PMID: 24038356 Free PMC article.