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Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.
Barrett JC, Clayton DG, Concannon P, Akolkar B, Cooper JD, Erlich HA, Julier C, Morahan G, Nerup J, Nierras C, Plagnol V, Pociot F, Schuilenburg H, Smyth DJ, Stevens H, Todd JA, Walker NM, Rich SS; Type 1 Diabetes Genetics Consortium. Barrett JC, et al. Among authors: walker nm. Nat Genet. 2009 Jun;41(6):703-7. doi: 10.1038/ng.381. Epub 2009 May 10. Nat Genet. 2009. PMID: 19430480 Free PMC article.
Comparative high-resolution analysis of linkage disequilibrium and tag single nucleotide polymorphisms between populations in the vitamin D receptor gene.
Nejentsev S, Godfrey L, Snook H, Rance H, Nutland S, Walker NM, Lam AC, Guja C, Ionescu-Tirgoviste C, Undlien DE, Rønningen KS, Tuomilehto-Wolf E, Tuomilehto J, Newport MJ, Clayton DG, Todd JA. Nejentsev S, et al. Among authors: walker nm. Hum Mol Genet. 2004 Aug 1;13(15):1633-9. doi: 10.1093/hmg/ddh169. Epub 2004 Jun 2. Hum Mol Genet. 2004. PMID: 15175274
Analysis of the vitamin D receptor gene sequence variants in type 1 diabetes.
Nejentsev S, Cooper JD, Godfrey L, Howson JM, Rance H, Nutland S, Walker NM, Guja C, Ionescu-Tirgovişte C, Savage DA, Undlien DE, Rønningen KS, Tuomilehto-Wolf E, Tuomilehto J, Gillespie KM, Ring SM, Strachan DP, Widmer B, Dunger D, Todd JA. Nejentsev S, et al. Among authors: walker nm. Diabetes. 2004 Oct;53(10):2709-12. doi: 10.2337/diabetes.53.10.2709. Diabetes. 2004. PMID: 15448105
Population structure, differential bias and genomic control in a large-scale, case-control association study.
Clayton DG, Walker NM, Smyth DJ, Pask R, Cooper JD, Maier LM, Smink LJ, Lam AC, Ovington NR, Stevens HE, Nutland S, Howson JM, Faham M, Moorhead M, Jones HB, Falkowski M, Hardenbol P, Willis TD, Todd JA. Clayton DG, et al. Among authors: walker nm. Nat Genet. 2005 Nov;37(11):1243-6. doi: 10.1038/ng1653. Epub 2005 Oct 9. Nat Genet. 2005. PMID: 16228001
Discovery, linkage disequilibrium and association analyses of polymorphisms of the immune complement inhibitor, decay-accelerating factor gene (DAF/CD55) in type 1 diabetes.
Taniguchi H, Lowe CE, Cooper JD, Smyth DJ, Bailey R, Nutland S, Healy BC, Lam AC, Burren O, Walker NM, Smink LJ, Wicker LS, Todd JA. Taniguchi H, et al. Among authors: walker nm. BMC Genet. 2006 Apr 20;7:22. doi: 10.1186/1471-2156-7-22. BMC Genet. 2006. PMID: 16626483 Free PMC article.
Interaction analysis of the CBLB and CTLA4 genes in type 1 diabetes.
Payne F, Cooper JD, Walker NM, Lam AC, Smink LJ, Nutland S, Stevens HE, Hutchings J, Todd JA. Payne F, et al. Among authors: walker nm. J Leukoc Biol. 2007 Mar;81(3):581-3. doi: 10.1189/jlb.0906577. Epub 2007 Jan 5. J Leukoc Biol. 2007. PMID: 17209142
Sequencing and association analysis of the type 1 diabetes-linked region on chromosome 10p12-q11.
Nejentsev S, Smink LJ, Smyth D, Bailey R, Lowe CE, Payne F, Masters J, Godfrey L, Lam A, Burren O, Stevens H, Nutland S, Walker NM, Smith A, Twells R, Barratt BJ, Wright C, French L, Chen Y, Deloukas P, Rogers J, Dunham I, Todd JA. Nejentsev S, et al. Among authors: walker nm. BMC Genet. 2007 May 17;8:24. doi: 10.1186/1471-2156-8-24. BMC Genet. 2007. PMID: 17509149 Free PMC article.
165 results