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ADAM17-dependent proteolysis of L-selectin promotes early clonal expansion of cytotoxic T cells.
Mohammed RN, Wehenkel SC, Galkina EV, Yates EK, Preece G, Newman A, Watson HA, Ohme J, Bridgeman JS, Durairaj RRP, Moon OR, Ladell K, Miners KL, Dolton G, Troeberg L, Kashiwagi M, Murphy G, Nagase H, Price DA, Matthews RJ, Knäuper V, Ager A. Mohammed RN, et al. Among authors: watson ha. Sci Rep. 2019 Apr 2;9(1):5487. doi: 10.1038/s41598-019-41811-z. Sci Rep. 2019. PMID: 30940840 Free PMC article.
L-Selectin Enhanced T Cells Improve the Efficacy of Cancer Immunotherapy.
Watson HA, Durairaj RRP, Ohme J, Alatsatianos M, Almutairi H, Mohammed RN, Vigar M, Reed SG, Paisey SJ, Marshall C, Gallimore A, Ager A. Watson HA, et al. Front Immunol. 2019 Jun 12;10:1321. doi: 10.3389/fimmu.2019.01321. eCollection 2019. Front Immunol. 2019. PMID: 31249570 Free PMC article.
LRG1 destabilizes tumor vessels and restricts immunotherapeutic potency.
O'Connor MN, Kallenberg DM, Camilli C, Pilotti C, Dritsoula A, Jackstadt R, Bowers CE, Watson HA, Alatsatianos M, Ohme J, Dowsett L, George J, Blackburn JWD, Wang X, Singhal M, Augustin HG, Ager A, Sansom OJ, Moss SE, Greenwood J. O'Connor MN, et al. Among authors: watson ha. Med. 2021 Nov 12;2(11):1231-1252.e10. doi: 10.1016/j.medj.2021.10.002. Epub 2021 Nov 3. Med. 2021. PMID: 35590198 Free PMC article.
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