Weedon MN - Search Results

1

Biological and clinical insights from genetics of insomnia symptoms.

Lane JM, Jones SE, Dashti HS, Wood AR, Aragam KG, van Hees VT, Strand LB, Winsvold BS, Wang H, Bowden J, Song Y, Patel K, Anderson SG, Beaumont RN, Bechtold DA, Cade BE, Haas M, Kathiresan S, Little MA, Luik AI, Loudon AS, Purcell S, Richmond RC, Scheer FAJL, Schormair B, Tyrrell J, Winkelman JW, Winkelmann J; HUNT All In Sleep; Hveem K, Zhao C, Nielsen JB, Willer CJ, Redline S, Spiegelhalder K, Kyle SD, Ray DW, Zwart JA, Brumpton B, Frayling TM, Lawlor DA, Rutter MK, Weedon MN, Saxena R. Lane JM, et al. Among authors: weedon mn. Nat Genet. 2019 Mar;51(3):387-393. doi: 10.1038/s41588-019-0361-7. Epub 2019 Feb 25. Nat Genet. 2019. PMID: 30804566 Free PMC article.

2

Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes.

Gloyn AL, Weedon MN, Owen KR, Turner MJ, Knight BA, Hitman G, Walker M, Levy JC, Sampson M, Halford S, McCarthy MI, Hattersley AT, Frayling TM. Gloyn AL, et al. Among authors: weedon mn. Diabetes. 2003 Feb;52(2):568-72. doi: 10.2337/diabetes.52.2.568. Diabetes. 2003. PMID: 12540637

3

Variants in the aromatase gene and on the Y-chromosome are not associated with adult height or insulin resistance in a UK population.

Weedon MN, Turner M, Knight B, Clark P, Hattersley AT, Frayling TM. Weedon MN, et al. Clin Endocrinol (Oxf). 2003 Aug;59(2):175-9. doi: 10.1046/j.1365-2265.2003.01797.x. Clin Endocrinol (Oxf). 2003. PMID: 12864794

4

Tall stories: the fundamental difficulties of genetic association studies.

Weedon MN, Hattersley AT, Frayling TM. Weedon MN, et al. Clin Endocrinol (Oxf). 2004 Jan;60(1):145-6. doi: 10.1111/j.1365-2265.2004.01950.x. Clin Endocrinol (Oxf). 2004. PMID: 14678302 No abstract available.

5

A large-scale association analysis of common variation of the HNF1alpha gene with type 2 diabetes in the U.K. Caucasian population.

Weedon MN, Owen KR, Shields B, Hitman G, Walker M, McCarthy MI, Hattersley AT, Frayling TM. Weedon MN, et al. Diabetes. 2005 Aug;54(8):2487-91. doi: 10.2337/diabetes.54.8.2487. Diabetes. 2005. PMID: 16046319

6

Common variations in the ALMS1 gene do not contribute to susceptibility to type 2 diabetes in a large white UK population.

Patel S, Minton JA, Weedon MN, Frayling TM, Ricketts C, Hitman GA, McCarthy MI, Hattersley AT, Walker M, Barrett TG. Patel S, et al. Among authors: weedon mn. Diabetologia. 2006 Jun;49(6):1209-13. doi: 10.1007/s00125-006-0227-2. Epub 2006 Apr 7. Diabetologia. 2006. PMID: 16601972

7

Functional variation in VEGF is not associated with type 2 diabetes in a United Kingdom Caucasian population.

Freathy RM, Weedon MN, Shields B, Hitman GA, Walker M, McCarthy MI, Hattersley AT, Frayling TM. Freathy RM, et al. Among authors: weedon mn. JOP. 2006 May 9;7(3):295-302. JOP. 2006. PMID: 16685110

8

The functional "KL-VS" variant of KLOTHO is not associated with type 2 diabetes in 5028 UK Caucasians.

Freathy RM, Weedon MN, Melzer D, Shields B, Hitman GA, Walker M, McCarthy MI, Hattersley AT, Frayling TM. Freathy RM, et al. Among authors: weedon mn. BMC Med Genet. 2006 Jun 5;7:51. doi: 10.1186/1471-2350-7-51. BMC Med Genet. 2006. PMID: 16753056 Free PMC article.

9

Assessment of the role of common genetic variation in the transient neonatal diabetes mellitus (TNDM) region in type 2 diabetes: a comparative genomic and tagging single nucleotide polymorphism approach.

Gloyn AL, Mackay DJ, Weedon MN, McCarthy MI, Walker M, Hitman G, Knight BA, Owen KR, Hattersley AT, Frayling TM. Gloyn AL, et al. Among authors: weedon mn. Diabetes. 2006 Aug;55(8):2272-6. doi: 10.2337/db06-0216. Diabetes. 2006. PMID: 16873690

10

Association analysis of 6,736 U.K. subjects provides replication and confirms TCF7L2 as a type 2 diabetes susceptibility gene with a substantial effect on individual risk.

Groves CJ, Zeggini E, Minton J, Frayling TM, Weedon MN, Rayner NW, Hitman GA, Walker M, Wiltshire S, Hattersley AT, McCarthy MI. Groves CJ, et al. Among authors: weedon mn. Diabetes. 2006 Sep;55(9):2640-4. doi: 10.2337/db06-0355. Diabetes. 2006. PMID: 16936215

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