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Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease.
Nielsen JB, Rom O, Surakka I, Graham SE, Zhou W, Roychowdhury T, Fritsche LG, Gagliano Taliun SA, Sidore C, Liu Y, Gabrielsen ME, Skogholt AH, Wolford B, Overton W, Zhao Y, Chen J, Zhang H, Hornsby WE, Acheampong A, Grooms A, Schaefer A, Zajac GJM, Villacorta L, Zhang J, Brumpton B, Løset M, Rai V, Lundegaard PR, Olesen MS, Taylor KD, Palmer ND, Chen YD, Choi SH, Lubitz SA, Ellinor PT, Barnes KC, Daya M, Rafaels N, Weiss ST, Lasky-Su J, Tracy RP, Vasan RS, Cupples LA, Mathias RA, Yanek LR, Becker LC, Peyser PA, Bielak LF, Smith JA, Aslibekyan S, Hidalgo BA, Arnett DK, Irvin MR, Wilson JG, Musani SK, Correa A, Rich SS, Guo X, Rotter JI, Konkle BA, Johnsen JM, Ashley-Koch AE, Telen MJ, Sheehan VA, Blangero J, Curran JE, Peralta JM, Montgomery C, Sheu WH, Chung RH, Schwander K, Nouraie SM, Gordeuk VR, Zhang Y, Kooperberg C, Reiner AP, Jackson RD, Bleecker ER, Meyers DA, Li X, Das S, Yu K, LeFaive J, Smith A, Blackwell T, Taliun D, Zollner S, Forer L, Schoenherr S, Fuchsberger C, Pandit A, Zawistowski M, Kheterpal S, Brummett CM, Natarajan P, Schlessinger D, Lee S, Kang HM, Cucca F, Holmen OL, Åsvold BO, Boehnke M, Kathiresan S, Abecasis GR, Chen YE, Willer CJ, Hveem K. Nielsen JB, et al. Among authors: weiss st. Nat Commun. 2020 Dec 18;11(1):6417. doi: 10.1038/s41467-020-20086-3. Nat Commun. 2020. PMID: 33339817 Free PMC article.
Asthma pharmacogenomics.
Hawkins GA, Weiss ST, Bleecker ER. Hawkins GA, et al. Among authors: weiss st. Immunol Allergy Clin North Am. 2005 Nov;25(4):723-42. doi: 10.1016/j.iac.2005.09.004. Immunol Allergy Clin North Am. 2005. PMID: 16257635
Clinical consequences of ADRbeta2 polymorphisms.
Hawkins GA, Weiss ST, Bleecker ER. Hawkins GA, et al. Among authors: weiss st. Pharmacogenomics. 2008 Mar;9(3):349-58. doi: 10.2217/14622416.9.3.349. Pharmacogenomics. 2008. PMID: 18303970 Review.
ARG1 is a novel bronchodilator response gene: screening and replication in four asthma cohorts.
Litonjua AA, Lasky-Su J, Schneiter K, Tantisira KG, Lazarus R, Klanderman B, Lima JJ, Irvin CG, Peters SP, Hanrahan JP, Liggett SB, Hawkins GA, Meyers DA, Bleecker ER, Lange C, Weiss ST. Litonjua AA, et al. Among authors: weiss st. Am J Respir Crit Care Med. 2008 Oct 1;178(7):688-94. doi: 10.1164/rccm.200709-1363OC. Epub 2008 Jul 10. Am J Respir Crit Care Med. 2008. PMID: 18617639 Free PMC article.
The glucocorticoid receptor heterocomplex gene STIP1 is associated with improved lung function in asthmatic subjects treated with inhaled corticosteroids.
Hawkins GA, Lazarus R, Smith RS, Tantisira KG, Meyers DA, Peters SP, Weiss ST, Bleecker ER. Hawkins GA, et al. Among authors: weiss st. J Allergy Clin Immunol. 2009 Jun;123(6):1376-83.e7. doi: 10.1016/j.jaci.2009.01.049. Epub 2009 Feb 28. J Allergy Clin Immunol. 2009. PMID: 19254810 Free PMC article.
999 results