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Small-Molecule Inhibitors Targeting Topoisomerase I as Novel Antituberculosis Agents.
Sandhaus S, Annamalai T, Welmaker G, Houghten RA, Paz C, Garcia PK, Andres A, Narula G, Rodrigues Felix C, Geden S, Netherton M, Gupta R, Rohde KH, Giulianotti MA, Tse-Dinh YC. Sandhaus S, et al. Among authors: welmaker g. Antimicrob Agents Chemother. 2016 Jun 20;60(7):4028-36. doi: 10.1128/AAC.00288-16. Print 2016 Jul. Antimicrob Agents Chemother. 2016. PMID: 27114277 Free PMC article.
Direct Phenotypic Screening in Mice: Identification of Individual, Novel Antinociceptive Compounds from a Library of 734,821 Pyrrolidine Bis-piperazines.
Houghten RA, Ganno ML, McLaughlin JP, Dooley CT, Eans SO, Santos RG, LaVoi T, Nefzi A, Welmaker G, Giulianotti MA, Toll L. Houghten RA, et al. Among authors: welmaker g. ACS Comb Sci. 2016 Jan 11;18(1):51-64. doi: 10.1021/acscombsci.5b00126. Epub 2016 Jan 5. ACS Comb Sci. 2016. PMID: 26651386 Free PMC article.
Shifting from the single to the multitarget paradigm in drug discovery.
Medina-Franco JL, Giulianotti MA, Welmaker GS, Houghten RA. Medina-Franco JL, et al. Among authors: welmaker gs. Drug Discov Today. 2013 May;18(9-10):495-501. doi: 10.1016/j.drudis.2013.01.008. Epub 2013 Jan 20. Drug Discov Today. 2013. PMID: 23340113 Free PMC article. Review.
Synthesis and 5-hydroxytryptamine (5-HT) activity of 2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5-(6H)ones and 2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoxalines.
Welmaker GS, Nelson JA, Sabalski JE, Sabb AL, Potoski JR, Graziano D, Kagan M, Coupet J, Dunlop J, Mazandarani H, Rosenzweig-Lipson S, Sukoff S, Zhang Y. Welmaker GS, et al. Bioorg Med Chem Lett. 2000 Sep 4;10(17):1991-4. doi: 10.1016/s0960-894x(00)00400-5. Bioorg Med Chem Lett. 2000. PMID: 10987434
14 results