Wen Z - Search Results

1

Uracil Nucleosides with Reactive Group at C5 Position: 5-(1-Halo-2-sulfonylvinyl)uridine Analogues.

Liang Y, Suzol SH, Wen Z, Artiles AG, Mathivathanan L, Raptis RG, Wnuk SF. Liang Y, et al. Among authors: wen z. Org Lett. 2016 Mar 18;18(6):1418-21. doi: 10.1021/acs.orglett.6b00346. Epub 2016 Mar 2. Org Lett. 2016. PMID: 26933954

2

Antiviral and Cytostatic Evaluation of 5-(1-Halo-2-sulfonylvinyl)- and 5-(2-Furyl)uracil Nucleosides.

Wen Z, Suzol SH, Peng J, Liang Y, Snoeck R, Andrei G, Liekens S, Wnuk SF. Wen Z, et al. Arch Pharm (Weinheim). 2017 Apr;350(3-4). doi: 10.1002/ardp.201700023. Epub 2017 Mar 17. Arch Pharm (Weinheim). 2017. PMID: 28304114

3

Pyrimidine Nucleosides with a Reactive (β-Chlorovinyl)sulfone or (β-Keto)sulfone Group at the C5 Position, Their Reactions with Nucleophiles and Electrophiles, and Their Polymerase-Catalyzed Incorporation into DNA.

Suzol SH, Howlader AH, Wen Z, Ren Y, Laverde EE, Garcia C, Liu Y, Wnuk SF. Suzol SH, et al. Among authors: wen z. ACS Omega. 2018 Apr 30;3(4):4276-4288. doi: 10.1021/acsomega.8b00584. Epub 2018 Apr 16. ACS Omega. 2018. PMID: 29732453 Free PMC article.

4

Electron-Mediated Aminyl and Iminyl Radicals from C5 Azido-Modified Pyrimidine Nucleosides Augment Radiation Damage to Cancer Cells.

Wen Z, Peng J, Tuttle PR, Ren Y, Garcia C, Debnath D, Rishi S, Hanson C, Ward S, Kumar A, Liu Y, Zhao W, Glazer PM, Liu Y, Sevilla MD, Adhikary A, Wnuk SF. Wen Z, et al. Org Lett. 2018 Dec 7;20(23):7400-7404. doi: 10.1021/acs.orglett.8b03035. Epub 2018 Nov 20. Org Lett. 2018. PMID: 30457873 Free PMC article.

5

Fluorescent 5-Pyrimidine and 8-Purine Nucleosides Modified with an N-Unsubstituted 1,2,3-Triazol-4-yl Moiety.

Wen Z, Tuttle PR, Howlader AH, Vasilyeva A, Gonzalez L, Tangar A, Lei R, Laverde EE, Liu Y, Miksovska J, Wnuk SF. Wen Z, et al. J Org Chem. 2019 Mar 15;84(6):3624-3631. doi: 10.1021/acs.joc.8b03135. Epub 2019 Mar 6. J Org Chem. 2019. PMID: 30806513 Free PMC article.

6

Exploration of Alternative Scaffolds for P2Y₁₄ Receptor Antagonists Containing a Biaryl Core.

Jung YH, Yu J, Wen Z, Salmaso V, Karcz TP, Phung NB, Chen Z, Duca S, Bennett JM, Dudas S, Salvemini D, Gao ZG, Cook DN, Jacobson KA. Jung YH, et al. Among authors: wen z. J Med Chem. 2020 Sep 10;63(17):9563-9589. doi: 10.1021/acs.jmedchem.0c00745. Epub 2020 Aug 6. J Med Chem. 2020. PMID: 32787142 Free PMC article.

7

Bridged Piperidine Analogues of a High Affinity Naphthalene-Based P2Y₁₄R Antagonist.

Wen Z, Salmaso V, Jung YH, Phung NB, Gopinatth V, Shah Q, Patterson AT, Randle JCR, Chen Z, Salvemini D, Lieberman DI, Whitehead GS, Karcz TP, Cook DN, Jacobson KA. Wen Z, et al. J Med Chem. 2022 Feb 24;65(4):3434-3459. doi: 10.1021/acs.jmedchem.1c01964. Epub 2022 Feb 3. J Med Chem. 2022. PMID: 35113556 Free PMC article.

8

Structure-Activity Relationship of Heterocyclic P2Y₁₄ Receptor Antagonists: Removal of the Zwitterionic Character with Piperidine Bioisosteres.

Jung YH, Salmaso V, Wen Z, Bennett JM, Phung NB, Lieberman DI, Gopinatth V, Randle JCR, Chen Z, Salvemini D, Karcz TP, Cook DN, Jacobson KA. Jung YH, et al. Among authors: wen z. J Med Chem. 2021 Apr 22;64(8):5099-5122. doi: 10.1021/acs.jmedchem.1c00164. Epub 2021 Mar 31. J Med Chem. 2021. PMID: 33787273 Free PMC article.

9

Effects of Purinergic Receptor Deletion or Pharmacologic Modulation on Pulmonary Inflammation in Mice.

Whitehead GS, Karcz TP, Tosh DK, Jung YH, Wen Z, Campbell RG, Gopinatth V, Gao ZG, Jacobson KA, Cook DN. Whitehead GS, et al. Among authors: wen z. ACS Pharmacol Transl Sci. 2022 Oct 5;5(10):973-984. doi: 10.1021/acsptsci.2c00128. eCollection 2022 Oct 14. ACS Pharmacol Transl Sci. 2022. PMID: 36268115 Free PMC article.

10

Prolonged elevated heart rate and 90-Day mortality in acute pancreatitis.

Xie S, Deng F, Zhang N, Wen Z, Ge C. Xie S, et al. Among authors: wen z. Sci Rep. 2024 Apr 28;14(1):9740. doi: 10.1038/s41598-024-59557-8. Sci Rep. 2024. PMID: 38679620

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