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Page 1
CXCR4 blockade induces atherosclerosis by affecting neutrophil function.
Bot I, Daissormont IT, Zernecke A, van Puijvelde GH, Kramp B, de Jager SC, Sluimer JC, Manca M, Hérias V, Westra MM, Bot M, van Santbrink PJ, van Berkel TJ, Su L, Skjelland M, Gullestad L, Kuiper J, Halvorsen B, Aukrust P, Koenen RR, Weber C, Biessen EA. Bot I, et al. Among authors: westra mm. J Mol Cell Cardiol. 2014 Sep;74:44-52. doi: 10.1016/j.yjmcc.2014.04.021. Epub 2014 May 8. J Mol Cell Cardiol. 2014. PMID: 24816217 Free PMC article.
Hematopoietic G-protein-coupled receptor kinase 2 deficiency decreases atherosclerotic lesion formation in LDL receptor-knockout mice.
Otten JJ, de Jager SC, Kavelaars A, Seijkens T, Bot I, Wijnands E, Beckers L, Westra MM, Bot M, Busch M, Bermudez B, van Berkel TJ, Heijnen CJ, Biessen EA. Otten JJ, et al. Among authors: westra mm. FASEB J. 2013 Jan;27(1):265-76. doi: 10.1096/fj.12-205351. Epub 2012 Oct 9. FASEB J. 2013. PMID: 23047899 Free PMC article.
Hematopoietic sphingosine 1-phosphate lyase deficiency decreases atherosclerotic lesion development in LDL-receptor deficient mice.
Bot M, Van Veldhoven PP, de Jager SC, Johnson J, Nijstad N, Van Santbrink PJ, Westra MM, Van Der Hoeven G, Gijbels MJ, Müller-Tidow C, Varga G, Tietge UJ, Kuiper J, Van Berkel TJ, Nofer JR, Bot I, Biessen EA. Bot M, et al. Among authors: westra mm. PLoS One. 2013 May 20;8(5):e63360. doi: 10.1371/journal.pone.0063360. Print 2013. PLoS One. 2013. PMID: 23700419 Free PMC article.
Low human and murine Mcl-1 expression leads to a pro-apoptotic plaque phenotype enriched in giant-cells.
Fontaine MAC, Westra MM, Bot I, Jin H, Franssen AJPM, Bot M, de Jager SCA, Dzhagalov I, He YW, van Vlijmen BJM, Gijbels MJJ, Reutelingsperger CP, van Berkel TJC, Sluimer JC, Temmerman L, Biessen EAL. Fontaine MAC, et al. Among authors: westra mm. Sci Rep. 2019 Oct 10;9(1):14547. doi: 10.1038/s41598-019-51020-3. Sci Rep. 2019. PMID: 31601924 Free PMC article.
Leukocyte cathepsin S is a potent regulator of both cell and matrix turnover in advanced atherosclerosis.
de Nooijer R, Bot I, von der Thüsen JH, Leeuwenburgh MA, Overkleeft HS, Kraaijeveld AO, Dorland R, van Santbrink PJ, van Heiningen SH, Westra MM, Kovanen PT, Jukema JW, van der Wall EE, van Berkel TJ, Shi GP, Biessen EA. de Nooijer R, et al. Among authors: westra mm. Arterioscler Thromb Vasc Biol. 2009 Feb;29(2):188-94. doi: 10.1161/ATVBAHA.108.181578. Epub 2008 Dec 18. Arterioscler Thromb Vasc Biol. 2009. PMID: 19095996
Magnetic resonance imaging contrast-enhancement with superparamagnetic iron oxide nanoparticles amplifies macrophage foam cell apoptosis in human and murine atherosclerosis.
Segers FME, Ruder AV, Westra MM, Lammers T, Dadfar SM, Roemhild K, Lam TS, Kooi ME, Cleutjens KBJM, Verheyen FK, Schurink GWH, Haenen GR, van Berkel TJC, Bot I, Halvorsen B, Sluimer JC, Biessen EAL. Segers FME, et al. Among authors: westra mm. Cardiovasc Res. 2023 Jan 18;118(17):3346-3359. doi: 10.1093/cvr/cvac032. Cardiovasc Res. 2023. PMID: 35325057 Free PMC article.