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A porcine model of neurofibromatosis type 1 that mimics the human disease.
White KA, Swier VJ, Cain JT, Kohlmeyer JL, Meyerholz DK, Tanas MR, Uthoff J, Hammond E, Li H, Rohret FA, Goeken A, Chan CH, Leidinger MR, Umesalma S, Wallace MR, Dodd RD, Panzer K, Tang AH, Darbro BW, Moutal A, Cai S, Li W, Bellampalli SS, Khanna R, Rogers CS, Sieren JC, Quelle DE, Weimer JM. White KA, et al. JCI Insight. 2018 Jun 21;3(12):e120402. doi: 10.1172/jci.insight.120402. eCollection 2018 Jun 21. JCI Insight. 2018. PMID: 29925695 Free PMC article.
Abbreviated exposure to hypoxia is sufficient to induce CNS dysmyelination, modulate spinal motor neuron composition, and impair motor development in neonatal mice.
Watzlawik JO, Kahoud RJ, O'Toole RJ, White KA, Ogden AR, Painter MM, Wootla B, Papke LM, Denic A, Weimer JM, Carey WA, Rodriguez M. Watzlawik JO, et al. Among authors: white ka. PLoS One. 2015 May 28;10(5):e0128007. doi: 10.1371/journal.pone.0128007. eCollection 2015. PLoS One. 2015. PMID: 26020269 Free PMC article.
A novel porcine model of ataxia telangiectasia reproduces neurological features and motor deficits of human disease.
Beraldi R, Chan CH, Rogers CS, Kovács AD, Meyerholz DK, Trantzas C, Lambertz AM, Darbro BW, Weber KL, White KA, Rheeden RV, Kruer MC, Dacken BA, Wang XJ, Davis BT, Rohret JA, Struzynski JT, Rohret FA, Weimer JM, Pearce DA. Beraldi R, et al. Among authors: white ka. Hum Mol Genet. 2015 Nov 15;24(22):6473-84. doi: 10.1093/hmg/ddv356. Epub 2015 Sep 15. Hum Mol Genet. 2015. PMID: 26374845 Free PMC article.
Searching for novel biomarkers using a mouse model of CLN3-Batten disease.
Timm D, Cain JT, Geraets RD, White KA, Koh SY, Kielian T, Pearce DA, Hastings ML, Weimer JM. Timm D, et al. Among authors: white ka. PLoS One. 2018 Aug 7;13(8):e0201470. doi: 10.1371/journal.pone.0201470. eCollection 2018. PLoS One. 2018. PMID: 30086172 Free PMC article.
Assessment of nociception and related quality-of-life measures in a porcine model of neurofibromatosis type 1.
Khanna R, Moutal A, White KA, Chefdeville A, Negrao de Assis P, Cai S, Swier VJ, Bellampalli SS, Giunta MD, Darbro BW, Quelle DE, Sieren JC, Wallace MR, Rogers CS, Meyerholz DK, Weimer JM. Khanna R, et al. Among authors: white ka. Pain. 2019 Nov;160(11):2473-2486. doi: 10.1097/j.pain.0000000000001648. Pain. 2019. PMID: 31246731 Free PMC article.
Gene Therapy Corrects Brain and Behavioral Pathologies in CLN6-Batten Disease.
Cain JT, Likhite S, White KA, Timm DJ, Davis SS, Johnson TB, Dennys-Rivers CN, Rinaldi F, Motti D, Corcoran S, Morales P, Pierson C, Hughes SM, Lee SY, Kaspar BK, Meyer K, Weimer JM. Cain JT, et al. Among authors: white ka. Mol Ther. 2019 Oct 2;27(10):1836-1847. doi: 10.1016/j.ymthe.2019.06.015. Epub 2019 Jul 10. Mol Ther. 2019. PMID: 31331814 Free PMC article.
254 results