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Identification of evolutionarily conserved genetic regulators of cellular aging.
Laschober GT, Ruli D, Hofer E, Muck C, Carmona-Gutierrez D, Ring J, Hutter E, Ruckenstuhl C, Micutkova L, Brunauer R, Jamnig A, Trimmel D, Herndler-Brandstetter D, Brunner S, Zenzmaier C, Sampson N, Breitenbach M, Fröhlich KU, Grubeck-Loebenstein B, Berger P, Wieser M, Grillari-Voglauer R, Thallinger GG, Grillari J, Trajanoski Z, Madeo F, Lepperdinger G, Jansen-Dürr P. Laschober GT, et al. Among authors: wieser m. Aging Cell. 2010 Dec;9(6):1084-97. doi: 10.1111/j.1474-9726.2010.00637.x. Epub 2010 Oct 28. Aging Cell. 2010. PMID: 20883526 Free PMC article.
miR-17, miR-19b, miR-20a, and miR-106a are down-regulated in human aging.
Hackl M, Brunner S, Fortschegger K, Schreiner C, Micutkova L, Mück C, Laschober GT, Lepperdinger G, Sampson N, Berger P, Herndler-Brandstetter D, Wieser M, Kühnel H, Strasser A, Rinnerthaler M, Breitenbach M, Mildner M, Eckhart L, Tschachler E, Trost A, Bauer JW, Papak C, Trajanoski Z, Scheideler M, Grillari-Voglauer R, Grubeck-Loebenstein B, Jansen-Dürr P, Grillari J. Hackl M, et al. Among authors: wieser m. Aging Cell. 2010 Apr;9(2):291-6. doi: 10.1111/j.1474-9726.2010.00549.x. Epub 2010 Jan 18. Aging Cell. 2010. PMID: 20089119 Free PMC article.
High levels of oncomiR-21 contribute to the senescence-induced growth arrest in normal human cells and its knock-down increases the replicative lifespan.
Dellago H, Preschitz-Kammerhofer B, Terlecki-Zaniewicz L, Schreiner C, Fortschegger K, Chang MW, Hackl M, Monteforte R, Kühnel H, Schosserer M, Gruber F, Tschachler E, Scheideler M, Grillari-Voglauer R, Grillari J, Wieser M. Dellago H, et al. Among authors: wieser m. Aging Cell. 2013 Jun;12(3):446-58. doi: 10.1111/acel.12069. Epub 2013 Apr 19. Aging Cell. 2013. PMID: 23496142 Free PMC article.
Secreted microvesicular miR-31 inhibits osteogenic differentiation of mesenchymal stem cells.
Weilner S, Schraml E, Wieser M, Messner P, Schneider K, Wassermann K, Micutkova L, Fortschegger K, Maier AB, Westendorp R, Resch H, Wolbank S, Redl H, Jansen-Dürr P, Pietschmann P, Grillari-Voglauer R, Grillari J. Weilner S, et al. Among authors: wieser m. Aging Cell. 2016 Aug;15(4):744-54. doi: 10.1111/acel.12484. Epub 2016 May 4. Aging Cell. 2016. PMID: 27146333 Free PMC article.
SNEV overexpression extends the life span of human endothelial cells.
Voglauer R, Chang MW, Dampier B, Wieser M, Baumann K, Sterovsky T, Schreiber M, Katinger H, Grillari J. Voglauer R, et al. Among authors: wieser m. Exp Cell Res. 2006 Apr 1;312(6):746-59. doi: 10.1016/j.yexcr.2005.11.025. Epub 2006 Jan 4. Exp Cell Res. 2006. PMID: 16388800
285 results