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A GWAS meta-analysis from 5 population-based cohorts implicates ion channel genes in the pathogenesis of irritable bowel syndrome.
Bonfiglio F, Henström M, Nag A, Hadizadeh F, Zheng T, Cenit MC, Tigchelaar E, Williams F, Reznichenko A, Ek WE, Rivera NV, Homuth G, Aghdassi AA, Kacprowski T, Männikkö M, Karhunen V, Bujanda L, Rafter J, Wijmenga C, Ronkainen J, Hysi P, Zhernakova A, D'Amato M. Bonfiglio F, et al. Among authors: wijmenga c. Neurogastroenterol Motil. 2018 Sep;30(9):e13358. doi: 10.1111/nmo.13358. Epub 2018 Apr 19. Neurogastroenterol Motil. 2018. PMID: 29673008
Habitual diet and diet quality in Irritable Bowel Syndrome: A case-control study.
Tigchelaar EF, Mujagic Z, Zhernakova A, Hesselink MAM, Meijboom S, Perenboom CWM, Masclee AAM, Wijmenga C, Feskens EJM, Jonkers DMAE. Tigchelaar EF, et al. Among authors: wijmenga c. Neurogastroenterol Motil. 2017 Dec;29(12). doi: 10.1111/nmo.13151. Epub 2017 Jul 17. Neurogastroenterol Motil. 2017. PMID: 28714091
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative.
Wang J, Kurilshikov A, Radjabzadeh D, Turpin W, Croitoru K, Bonder MJ, Jackson MA, Medina-Gomez C, Frost F, Homuth G, Rühlemann M, Hughes D, Kim HN; MiBioGen Consortium Initiative; Spector TD, Bell JT, Steves CJ, Timpson N, Franke A, Wijmenga C, Meyer K, Kacprowski T, Franke L, Paterson AD, Raes J, Kraaij R, Zhernakova A. Wang J, et al. Among authors: wijmenga c. Microbiome. 2018 Jun 8;6(1):101. doi: 10.1186/s40168-018-0479-3. Microbiome. 2018. PMID: 29880062 Free PMC article.
Gut microbiota composition associated with stool consistency.
Tigchelaar EF, Bonder MJ, Jankipersadsing SA, Fu J, Wijmenga C, Zhernakova A. Tigchelaar EF, et al. Among authors: wijmenga c. Gut. 2016 Mar;65(3):540-2. doi: 10.1136/gutjnl-2015-310328. Epub 2015 Aug 14. Gut. 2016. PMID: 26276682 No abstract available.
Genetic variants in the region harbouring IL2/IL21 associated with ulcerative colitis.
Festen EA, Goyette P, Scott R, Annese V, Zhernakova A, Lian J, Lefèbvre C, Brant SR, Cho JH, Silverberg MS, Taylor KD, de Jong DJ, Stokkers PC, Mcgovern D, Palmieri O, Achkar JP, Xavier RJ, Daly MJ, Duerr RH, Wijmenga C, Weersma RK, Rioux JD. Festen EA, et al. Among authors: wijmenga c. Gut. 2009 Jun;58(6):799-804. doi: 10.1136/gut.2008.166918. Epub 2009 Feb 6. Gut. 2009. PMID: 19201773 Free PMC article.
A combination of fecal calprotectin and human beta-defensin 2 facilitates diagnosis and monitoring of inflammatory bowel disease.
Gacesa R, Vich Vila A, Collij V, Mujagic Z, Kurilshikov A, Voskuil MD, Festen EAM, Wijmenga C, Jonkers DMAE, Dijkstra G, Fu J, Zhernakova A, Imhann F, Weersma RK. Gacesa R, et al. Among authors: wijmenga c. Gut Microbes. 2021 Jan-Dec;13(1):1943288. doi: 10.1080/19490976.2021.1943288. Gut Microbes. 2021. PMID: 34313538 Free PMC article.
Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.
Trynka G, Zhernakova A, Romanos J, Franke L, Hunt KA, Turner G, Bruinenberg M, Heap GA, Platteel M, Ryan AW, de Kovel C, Holmes GK, Howdle PD, Walters JR, Sanders DS, Mulder CJ, Mearin ML, Verbeek WH, Trimble V, Stevens FM, Kelleher D, Barisani D, Bardella MT, McManus R, van Heel DA, Wijmenga C. Trynka G, et al. Among authors: wijmenga c. Gut. 2009 Aug;58(8):1078-83. doi: 10.1136/gut.2008.169052. Epub 2009 Feb 24. Gut. 2009. PMID: 19240061
Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs.
Ricaño-Ponce I, Zhernakova DV, Deelen P, Luo O, Li X, Isaacs A, Karjalainen J, Di Tommaso J, Borek ZA, Zorro MM, Gutierrez-Achury J, Uitterlinden AG, Hofman A, van Meurs J; BIOS Consortium; Lifelines Cohort Study; Netea MG, Jonkers IH, Withoff S, van Duijn CM, Li Y, Ruan Y, Franke L, Wijmenga C, Kumar V. Ricaño-Ponce I, et al. Among authors: wijmenga c. J Autoimmun. 2016 Apr;68:62-74. doi: 10.1016/j.jaut.2016.01.002. Epub 2016 Feb 18. J Autoimmun. 2016. PMID: 26898941 Free PMC article.
703 results