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Cerebellar ataxia and Purkinje cell dysfunction caused by Ca2+-activated K+ channel deficiency.
Sausbier M, Hu H, Arntz C, Feil S, Kamm S, Adelsberger H, Sausbier U, Sailer CA, Feil R, Hofmann F, Korth M, Shipston MJ, Knaus HG, Wolfer DP, Pedroarena CM, Storm JF, Ruth P. Sausbier M, et al. Among authors: wolfer dp. Proc Natl Acad Sci U S A. 2004 Jun 22;101(25):9474-8. doi: 10.1073/pnas.0401702101. Epub 2004 Jun 11. Proc Natl Acad Sci U S A. 2004. PMID: 15194823 Free PMC article.
Modeling familial Danish dementia in mice supports the concept of the amyloid hypothesis of Alzheimer's disease.
Coomaraswamy J, Kilger E, Wölfing H, Schäfer C, Kaeser SA, Wegenast-Braun BM, Hefendehl JK, Wolburg H, Mazzella M, Ghiso J, Goedert M, Akiyama H, Garcia-Sierra F, Wolfer DP, Mathews PM, Jucker M. Coomaraswamy J, et al. Among authors: wolfer dp. Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7969-74. doi: 10.1073/pnas.1001056107. Epub 2010 Apr 12. Proc Natl Acad Sci U S A. 2010. PMID: 20385796 Free PMC article.
Loss of the limbic mineralocorticoid receptor impairs behavioral plasticity.
Berger S, Wolfer DP, Selbach O, Alter H, Erdmann G, Reichardt HM, Chepkova AN, Welzl H, Haas HL, Lipp HP, Schütz G. Berger S, et al. Among authors: wolfer dp. Proc Natl Acad Sci U S A. 2006 Jan 3;103(1):195-200. doi: 10.1073/pnas.0503878102. Epub 2005 Dec 20. Proc Natl Acad Sci U S A. 2006. PMID: 16368758 Free PMC article.
Mice lacking the gene encoding tissue-type plasminogen activator show a selective interference with late-phase long-term potentiation in both Schaffer collateral and mossy fiber pathways.
Huang YY, Bach ME, Lipp HP, Zhuo M, Wolfer DP, Hawkins RD, Schoonjans L, Kandel ER, Godfraind JM, Mulligan R, Collen D, Carmeliet P. Huang YY, et al. Among authors: wolfer dp. Proc Natl Acad Sci U S A. 1996 Aug 6;93(16):8699-704. doi: 10.1073/pnas.93.16.8699. Proc Natl Acad Sci U S A. 1996. PMID: 8710934 Free PMC article.
Early Aβ reduction prevents progression of cerebral amyloid angiopathy.
Schelle J, Wegenast-Braun BM, Fritschi SK, Kaeser SA, Jährling N, Eicke D, Skodras A, Beschorner N, Obermueller U, Häsler LM, Wolfer DP, Mueggler T, Shimshek DR, Neumann U, Dodt HU, Staufenbiel M, Jucker M. Schelle J, et al. Among authors: wolfer dp. Ann Neurol. 2019 Oct;86(4):561-571. doi: 10.1002/ana.25562. Epub 2019 Aug 19. Ann Neurol. 2019. PMID: 31359452
Defective limbic system in mice lacking the tailless gene.
Monaghan AP, Bock D, Gass P, Schwäger A, Wolfer DP, Lipp HP, Schütz G. Monaghan AP, et al. Among authors: wolfer dp. Nature. 1997 Dec 4;390(6659):515-7. doi: 10.1038/37364. Nature. 1997. PMID: 9394001
158 results