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253 results

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BL-8040, a CXCR4 antagonist, in combination with pembrolizumab and chemotherapy for pancreatic cancer: the COMBAT trial.
Bockorny B, Semenisty V, Macarulla T, Borazanci E, Wolpin BM, Stemmer SM, Golan T, Geva R, Borad MJ, Pedersen KS, Park JO, Ramirez RA, Abad DG, Feliu J, Muñoz A, Ponz-Sarvise M, Peled A, Lustig TM, Bohana-Kashtan O, Shaw SM, Sorani E, Chaney M, Kadosh S, Vainstein Haras A, Von Hoff DD, Hidalgo M. Bockorny B, et al. Among authors: wolpin bm. Nat Med. 2020 Jun;26(6):878-885. doi: 10.1038/s41591-020-0880-x. Epub 2020 May 25. Nat Med. 2020. PMID: 32451495 Clinical Trial.
Adjuvant treatment of colorectal cancer.
Wolpin BM, Meyerhardt JA, Mamon HJ, Mayer RJ. Wolpin BM, et al. CA Cancer J Clin. 2007 May-Jun;57(3):168-85. doi: 10.3322/canjclin.57.3.168. CA Cancer J Clin. 2007. PMID: 17507442 Free article. Review.
Global, multicenter, randomized, phase II trial of gemcitabine and gemcitabine plus AGS-1C4D4 in patients with previously untreated, metastatic pancreatic cancer.
Wolpin BM, O'Reilly EM, Ko YJ, Blaszkowsky LS, Rarick M, Rocha-Lima CM, Ritch P, Chan E, Spratlin J, Macarulla T, McWhirter E, Pezet D, Lichinitser M, Roman L, Hartford A, Morrison K, Jackson L, Vincent M, Reyno L, Hidalgo M. Wolpin BM, et al. Ann Oncol. 2013 Jul;24(7):1792-1801. doi: 10.1093/annonc/mdt066. Epub 2013 Feb 28. Ann Oncol. 2013. PMID: 23448807 Free PMC article. Clinical Trial.
Pancreatic Cancer.
Wolpin BM. Wolpin BM. Hematol Oncol Clin North Am. 2015 Aug;29(4):xiii-xiv. doi: 10.1016/j.hoc.2015.06.002. Hematol Oncol Clin North Am. 2015. PMID: 26226911 No abstract available.
Altered exocrine function can drive adipose wasting in early pancreatic cancer.
Danai LV, Babic A, Rosenthal MH, Dennstedt EA, Muir A, Lien EC, Mayers JR, Tai K, Lau AN, Jones-Sali P, Prado CM, Petersen GM, Takahashi N, Sugimoto M, Yeh JJ, Lopez N, Bardeesy N, Fernandez-Del Castillo C, Liss AS, Koong AC, Bui J, Yuan C, Welch MW, Brais LK, Kulke MH, Dennis C, Clish CB, Wolpin BM, Vander Heiden MG. Danai LV, et al. Among authors: wolpin bm. Nature. 2018 Jun;558(7711):600-604. doi: 10.1038/s41586-018-0235-7. Epub 2018 Jun 20. Nature. 2018. PMID: 29925948 Free PMC article.
Phase 1b study of a small molecule antagonist of human chemokine (C-C motif) receptor 2 (PF-04136309) in combination with nab-paclitaxel/gemcitabine in first-line treatment of metastatic pancreatic ductal adenocarcinoma.
Noel M, O'Reilly EM, Wolpin BM, Ryan DP, Bullock AJ, Britten CD, Linehan DC, Belt BA, Gamelin EC, Ganguly B, Yin D, Joh T, Jacobs IA, Taylor CT, Lowery MA. Noel M, et al. Among authors: wolpin bm. Invest New Drugs. 2020 Jun;38(3):800-811. doi: 10.1007/s10637-019-00830-3. Epub 2019 Jul 12. Invest New Drugs. 2020. PMID: 31297636 Free PMC article. Clinical Trial.
Polymerase θ inhibition activates the cGAS-STING pathway and cooperates with immune checkpoint blockade in models of BRCA-deficient cancer.
Patterson-Fortin J, Jadhav H, Pantelidou C, Phan T, Grochala C, Mehta AK, Guerriero JL, Wulf GM, Wolpin BM, Stanger BZ, Aguirre AJ, Cleary JM, D'Andrea AD, Shapiro GI. Patterson-Fortin J, et al. Among authors: wolpin bm. Nat Commun. 2023 Mar 13;14(1):1390. doi: 10.1038/s41467-023-37096-6. Nat Commun. 2023. PMID: 36914658 Free PMC article. Retracted.
Pancreatic cancer is associated with medication changes prior to clinical diagnosis.
Zhang Y, Wang QL, Yuan C, Lee AA, Babic A, Ng K, Perez K, Nowak JA, Lagergren J, Stampfer MJ, Giovannucci EL, Sander C, Rosenthal MH, Kraft P, Wolpin BM. Zhang Y, et al. Among authors: wolpin bm. Nat Commun. 2023 Apr 28;14(1):2437. doi: 10.1038/s41467-023-38088-2. Nat Commun. 2023. PMID: 37117188 Free PMC article.
A deep learning algorithm to predict risk of pancreatic cancer from disease trajectories.
Placido D, Yuan B, Hjaltelin JX, Zheng C, Haue AD, Chmura PJ, Yuan C, Kim J, Umeton R, Antell G, Chowdhury A, Franz A, Brais L, Andrews E, Marks DS, Regev A, Ayandeh S, Brophy MT, Do NV, Kraft P, Wolpin BM, Rosenthal MH, Fillmore NR, Brunak S, Sander C. Placido D, et al. Among authors: wolpin bm. Nat Med. 2023 May;29(5):1113-1122. doi: 10.1038/s41591-023-02332-5. Epub 2023 May 8. Nat Med. 2023. PMID: 37156936 Free PMC article.
253 results