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Page 1
Genetic predisposition to PEG-asparaginase hypersensitivity in children treated according to NOPHO ALL2008.
Højfeldt SG, Wolthers BO, Tulstrup M, Abrahamsson J, Gupta R, Harila-Saari A, Heyman M, Henriksen LT, Jónsson ÒG, Lähteenmäki PM, Lund B, Pruunsild K, Vaitkeviciene G, Schmiegelow K, Albertsen BK; Nordic Society of Paediatric Haematology Oncology (NOPHO) group. Højfeldt SG, et al. Among authors: wolthers bo. Br J Haematol. 2019 Feb;184(3):405-417. doi: 10.1111/bjh.15660. Epub 2018 Nov 18. Br J Haematol. 2019. PMID: 30450575 Free article. Clinical Trial.
Asparaginase-Associated Pancreatitis in Acute Lymphoblastic Leukemia: Results From the NOPHO ALL2008 Treatment of Patients 1-45 Years of Age.
Rank CU, Wolthers BO, Grell K, Albertsen BK, Frandsen TL, Overgaard UM, Toft N, Nielsen OJ, Wehner PS, Harila-Saari A, Heyman MM, Malmros J, Abrahamsson J, Norén-Nyström U, Tomaszewska-Toporska B, Lund B, Jarvis KB, Quist-Paulsen P, Vaitkevičienė GE, Griškevičius L, Taskinen M, Wartiovaara-Kautto U, Lepik K, Punab M, Jónsson ÓG, Schmiegelow K. Rank CU, et al. Among authors: wolthers bo. J Clin Oncol. 2020 Jan 10;38(2):145-154. doi: 10.1200/JCO.19.02208. Epub 2019 Nov 26. J Clin Oncol. 2020. PMID: 31770057 Free PMC article.
Relapse risk following truncation of pegylated asparaginase in childhood acute lymphoblastic leukemia.
Gottschalk Højfeldt S, Grell K, Abrahamsson J, Lund B, Vettenranta K, Jónsson ÓG, Frandsen TL, Wolthers BO, Marquart HV, Vaitkeviciene G, Lepik K, Heyman M, Schmiegelow K, Albertsen BK. Gottschalk Højfeldt S, et al. Among authors: wolthers bo. Blood. 2021 Apr 29;137(17):2373-2382. doi: 10.1182/blood.2020006583. Blood. 2021. PMID: 33150360 Free article. Clinical Trial.
Asparaginase enzyme activity levels and toxicity in childhood acute lymphoblastic leukemia: a NOPHO ALL2008 study.
Lynggaard LS, Rank CU, Hansen SN, Gottschalk Højfeldt S, Henriksen LT, Jarvis KB, Ranta S, Niinimäki R, Harila-Saari A, Wolthers BO, Frandsen TL, Heyman M, Schmiegelow K, Albertsen BK. Lynggaard LS, et al. Among authors: wolthers bo. Blood Adv. 2022 Jan 11;6(1):138-147. doi: 10.1182/bloodadvances.2021005631. Blood Adv. 2022. PMID: 34625787 Free PMC article.
Effects of germline DHFR and FPGS variants on methotrexate metabolism and relapse of leukemia.
Tulstrup M, Moriyama T, Jiang C, Grosjean M, Nersting J, Abrahamsson J, Grell K, Hjalgrim LL, Jónsson ÓG, Kanerva J, Lund B, Nielsen SN, Nielsen RL, Overgaard U, Quist-Paulsen P, Pruunsild K, Vaitkeviciene G, Wolthers BO, Zhang H, Gupta R, Yang JJ, Schmiegelow K. Tulstrup M, et al. Among authors: wolthers bo. Blood. 2020 Sep 3;136(10):1161-1168. doi: 10.1182/blood.2020005064. Blood. 2020. PMID: 32391884 Free PMC article.
Acute central nervous system toxicity during treatment of pediatric acute lymphoblastic leukemia: phenotypes, risk factors and genotypes.
Anastasopoulou S, Nielsen RL, Als-Nielsen B, Banerjee J, Eriksson MA, Helenius M, Heyman MM, Johannsdottir IM, Jonsson OG, MacGregor S, Mateos MK, Mayoh C, Mikkel S, Myrberg IH, Niinimäki R, Schmiegelow K, Taskinen M, Vaitkeviciene G, Warnqvist A, Wolthers B, Harila-Saari A, Ranta S. Anastasopoulou S, et al. Haematologica. 2022 Oct 1;107(10):2318-2328. doi: 10.3324/haematol.2021.280016. Haematologica. 2022. PMID: 35354251 Free PMC article.
Trypsin-encoding PRSS1-PRSS2 variations influence the risk of asparaginase-associated pancreatitis in children with acute lymphoblastic leukemia: a Ponte di Legno toxicity working group report.
Wolthers BO, Frandsen TL, Patel CJ, Abaji R, Attarbaschi A, Barzilai S, Colombini A, Escherich G, Grosjean M, Krajinovic M, Larsen E, Liang DC, Möricke A, Rasmussen KK, Samarasinghe S, Silverman LB, van der Sluis IM, Stanulla M, Tulstrup M, Yadav R, Yang W, Zapotocka E, Gupta R, Schmiegelow K; Ponte di Legno toxicity working group. Wolthers BO, et al. Haematologica. 2019 Mar;104(3):556-563. doi: 10.3324/haematol.2018.199356. Epub 2018 Nov 22. Haematologica. 2019. PMID: 30467200 Free PMC article.
Can Machine Learning Models Predict Asparaginase-associated Pancreatitis in Childhood Acute Lymphoblastic Leukemia.
Nielsen RL, Wolthers BO, Helenius M, Albertsen BK, Clemmensen L, Nielsen K, Kanerva J, Niinimäki R, Frandsen TL, Attarbaschi A, Barzilai S, Colombini A, Escherich G, Aytan-Aktug D, Liu HC, Möricke A, Samarasinghe S, van der Sluis IM, Stanulla M, Tulstrup M, Yadav R, Zapotocka E, Schmiegelow K, Gupta R. Nielsen RL, et al. Among authors: wolthers bo. J Pediatr Hematol Oncol. 2022 Apr 1;44(3):e628-e636. doi: 10.1097/MPH.0000000000002292. J Pediatr Hematol Oncol. 2022. PMID: 35226426 Free PMC article.
30 results