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Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.
Howard DM, Adams MJ, Clarke TK, Hafferty JD, Gibson J, Shirali M, Coleman JRI, Hagenaars SP, Ward J, Wigmore EM, Alloza C, Shen X, Barbu MC, Xu EY, Whalley HC, Marioni RE, Porteous DJ, Davies G, Deary IJ, Hemani G, Berger K, Teismann H, Rawal R, Arolt V, Baune BT, Dannlowski U, Domschke K, Tian C, Hinds DA; 23andMe Research Team; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Trzaskowski M, Byrne EM, Ripke S, Smith DJ, Sullivan PF, Wray NR, Breen G, Lewis CM, McIntosh AM. Howard DM, et al. Among authors: wray nr. Nat Neurosci. 2019 Mar;22(3):343-352. doi: 10.1038/s41593-018-0326-7. Epub 2019 Feb 4. Nat Neurosci. 2019. PMID: 30718901 Free PMC article.
Haplotype analysis and a novel allele-sharing method refines a chromosome 4p locus linked to bipolar affective disorder.
Le Hellard S, Lee AJ, Underwood S, Thomson PA, Morris SW, Torrance HS, Anderson SM, Adams RR, Navarro P, Christoforou A, Houlihan LM, Detera-Wadleigh S, Owen MJ, Asherson P, Muir WJ, Blackwood DH, Wray NR, Porteous DJ, Evans KL. Le Hellard S, et al. Among authors: wray nr. Biol Psychiatry. 2007 Mar 15;61(6):797-805. doi: 10.1016/j.biopsych.2006.06.029. Epub 2006 Sep 25. Biol Psychiatry. 2007. PMID: 16996484
Anxiety and comorbid measures associated with PLXNA2.
Wray NR, James MR, Mah SP, Nelson M, Andrews G, Sullivan PF, Montgomery GW, Birley AJ, Braun A, Martin NG. Wray NR, et al. Arch Gen Psychiatry. 2007 Mar;64(3):318-26. doi: 10.1001/archpsyc.64.3.318. Arch Gen Psychiatry. 2007. PMID: 17339520
Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo.
Sullivan PF, de Geus EJ, Willemsen G, James MR, Smit JH, Zandbelt T, Arolt V, Baune BT, Blackwood D, Cichon S, Coventry WL, Domschke K, Farmer A, Fava M, Gordon SD, He Q, Heath AC, Heutink P, Holsboer F, Hoogendijk WJ, Hottenga JJ, Hu Y, Kohli M, Lin D, Lucae S, Macintyre DJ, Maier W, McGhee KA, McGuffin P, Montgomery GW, Muir WJ, Nolen WA, Nöthen MM, Perlis RH, Pirlo K, Posthuma D, Rietschel M, Rizzu P, Schosser A, Smit AB, Smoller JW, Tzeng JY, van Dyck R, Verhage M, Zitman FG, Martin NG, Wray NR, Boomsma DI, Penninx BW. Sullivan PF, et al. Among authors: wray nr. Mol Psychiatry. 2009 Apr;14(4):359-75. doi: 10.1038/mp.2008.125. Epub 2008 Dec 9. Mol Psychiatry. 2009. PMID: 19065144 Free PMC article.
Common polygenic variation contributes to risk of schizophrenia and bipolar disorder.
International Schizophrenia Consortium; Purcell SM, Wray NR, Stone JL, Visscher PM, O'Donovan MC, Sullivan PF, Sklar P. International Schizophrenia Consortium, et al. Among authors: wray nr. Nature. 2009 Aug 6;460(7256):748-52. doi: 10.1038/nature08185. Epub 2009 Jul 1. Nature. 2009. PMID: 19571811 Free PMC article.
410 results