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Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform.
Moraes CB, Witt G, Kuzikov M, Ellinger B, Calogeropoulou T, Prousis KC, Mangani S, Di Pisa F, Landi G, Iacono LD, Pozzi C, Freitas-Junior LH, Dos Santos Pascoalino B, Bertolacini CP, Behrens B, Keminer O, Leu J, Wolf M, Reinshagen J, Cordeiro-da-Silva A, Santarem N, Venturelli A, Wrigley S, Karunakaran D, Kebede B, Pöhner I, Müller W, Panecka-Hofman J, Wade RC, Fenske M, Clos J, Alunda JM, Corral MJ, Uliassi E, Bolognesi ML, Linciano P, Quotadamo A, Ferrari S, Santucci M, Borsari C, Costi MP, Gul S. Moraes CB, et al. Among authors: wrigley s. SLAS Discov. 2019 Mar;24(3):346-361. doi: 10.1177/2472555218823171. SLAS Discov. 2019. PMID: 30784368 Free PMC article.
Mining for natural product antileishmanials in a fungal extract library.
Mbekeani AJ, Jones RS, Bassas Llorens M, Elliot J, Regnault C, Barrett MP, Steele J, Kebede B, Wrigley SK, Evans L, Denny PW. Mbekeani AJ, et al. Among authors: wrigley sk. Int J Parasitol Drugs Drug Resist. 2019 Dec;11:118-128. doi: 10.1016/j.ijpddr.2019.05.003. Epub 2019 Jun 11. Int J Parasitol Drugs Drug Resist. 2019. PMID: 31208892 Free PMC article.
Biotransformation: Impact and Application of Metabolism in Drug Discovery.
Shanu-Wilson J, Evans L, Wrigley S, Steele J, Atherton J, Boer J. Shanu-Wilson J, et al. Among authors: wrigley s. ACS Med Chem Lett. 2020 Aug 28;11(11):2087-2107. doi: 10.1021/acsmedchemlett.0c00202. eCollection 2020 Nov 12. ACS Med Chem Lett. 2020. PMID: 33214818 Free PMC article.
Novel streptopyrroles from Streptomyces rimosus with bacterial protein histidine kinase inhibitory and antimicrobial activities.
Trew SJ, Wrigley SK, Pairet L, Sohal J, Shanu-Wilson P, Hayes MA, Martin SM, Manohar RN, Chicarelli-Robinson MI, Kau DA, Byrne CV, Wellington EM, Moloney JM, Howard J, Hupe D, Olson ER. Trew SJ, et al. Among authors: wrigley sk. J Antibiot (Tokyo). 2000 Jan;53(1):1-11. doi: 10.7164/antibiotics.53.1. J Antibiot (Tokyo). 2000. PMID: 10724001 Free article.
A novel (6S)-4,6-dimethyldodeca-2E,4E-dienoyl ester of phomalactone and related alpha-pyrone esters from a Phomopsis sp. with cytokine production inhibitory activity.
Wrigley SK, Sadeghi R, Bahl S, Whiting AJ, Ainsworth AM, Martin SM, Katzer W, Ford R, Kau DA, Robinson N, Hayes MA, Elcock C, Mander T, Moore M. Wrigley SK, et al. J Antibiot (Tokyo). 1999 Oct;52(10):862-72. doi: 10.7164/antibiotics.52.862. J Antibiot (Tokyo). 1999. PMID: 10604755 Free article.
XR651, a novel naphthacene-5,12-dione.
Bahl S, Martin S, Rawlins P, Sadeghi R, Smith PM, Steel J, Shanu-Wilson P, Wood KA, Wrigley SK. Bahl S, et al. Among authors: wrigley sk. J Antibiot (Tokyo). 1997 Feb;50(2):169-71. doi: 10.7164/antibiotics.50.169. J Antibiot (Tokyo). 1997. PMID: 9099228 Free article. No abstract available.
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