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Developing the IVIG biomimetic, hexa-Fc, for drug and vaccine applications.
Czajkowsky DM, Andersen JT, Fuchs A, Wilson TJ, Mekhaiel D, Colonna M, He J, Shao Z, Mitchell DA, Wu G, Dell A, Haslam S, Lloyd KA, Moore SC, Sandlie I, Blundell PA, Pleass RJ. Czajkowsky DM, et al. Among authors: wu g. Sci Rep. 2015 Apr 27;5:9526. doi: 10.1038/srep09526. Sci Rep. 2015. PMID: 25912958 Free PMC article.
The zebrafish galectins Drgal1-L2 and Drgal3-L1 bind in vitro to the infectious hematopoietic necrosis virus (IHNV) glycoprotein and reduce viral adhesion to fish epithelial cells.
Nita-Lazar M, Mancini J, Feng C, González-Montalbán N, Ravindran C, Jackson S, de Las Heras-Sánchez A, Giomarelli B, Ahmed H, Haslam SM, Wu G, Dell A, Ammayappan A, Vakharia VN, Vasta GR. Nita-Lazar M, et al. Among authors: wu g. Dev Comp Immunol. 2016 Feb;55:241-252. doi: 10.1016/j.dci.2015.09.007. Epub 2015 Sep 30. Dev Comp Immunol. 2016. PMID: 26429411 Free PMC article.
Hypomorphic homozygous mutations in phosphoglucomutase 3 (PGM3) impair immunity and increase serum IgE levels.
Sassi A, Lazaroski S, Wu G, Haslam SM, Fliegauf M, Mellouli F, Patiroglu T, Unal E, Ozdemir MA, Jouhadi Z, Khadir K, Ben-Khemis L, Ben-Ali M, Ben-Mustapha I, Borchani L, Pfeifer D, Jakob T, Khemiri M, Asplund AC, Gustafsson MO, Lundin KE, Falk-Sörqvist E, Moens LN, Gungor HE, Engelhardt KR, Dziadzio M, Stauss H, Fleckenstein B, Meier R, Prayitno K, Maul-Pavicic A, Schaffer S, Rakhmanov M, Henneke P, Kraus H, Eibel H, Kölsch U, Nadifi S, Nilsson M, Bejaoui M, Schäffer AA, Smith CI, Dell A, Barbouche MR, Grimbacher B. Sassi A, et al. Among authors: wu g. J Allergy Clin Immunol. 2014 May;133(5):1410-9, 1419.e1-13. doi: 10.1016/j.jaci.2014.02.025. Epub 2014 Apr 1. J Allergy Clin Immunol. 2014. PMID: 24698316 Free PMC article. Clinical Trial.
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