Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

82 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Discovery of a potent, orally bioavailable beta(3) adrenergic receptor agonist, (R)-N-[4-[2-[[2-hydroxy-2-(3-pyridinyl)ethyl]amino]ethyl]phenyl]-4-[4 -[4-(trifluoromethyl)phenyl]thiazol-2-yl]benzenesulfonamide.
Mathvink RJ, Tolman JS, Chitty D, Candelore MR, Cascieri MA, Colwell LF Jr, Deng L, Feeney WP, Forrest MJ, Hom GJ, MacIntyre DE, Miller RR, Stearns RA, Tota L, Wyvratt MJ, Fisher MH, Weber AE. Mathvink RJ, et al. Among authors: wyvratt mj. J Med Chem. 2000 Oct 19;43(21):3832-6. doi: 10.1021/jm000286i. J Med Chem. 2000. PMID: 11052788
A potent, orally bioavailable benzazepinone growth hormone secretagogue.
DeVita RJ, Bochis R, Frontier AJ, Kotliar A, Fisher MH, Schoen WR, Wyvratt MJ, Cheng K, Chan WW, Butler B, Jacks TM, Hickey GJ, Schleim KD, Leung K, Chen Z, Chiu SL, Feeney WP, Cunningham PK, Smith RG. DeVita RJ, et al. Among authors: wyvratt mj. J Med Chem. 1998 May 7;41(10):1716-28. doi: 10.1021/jm970816j. J Med Chem. 1998. PMID: 9572898
3-Pyridylethanolamines: potent and selective human beta 3 adrenergic receptor agonists.
Naylor EM, Colandrea VJ, Candelore MR, Cascieri MA, Colwell LF Jr, Deng L, Feeney WP, Forrest MJ, Hom GJ, MacIntyre DE, Strader CD, Tota L, Wang PR, Wyvratt MJ, Fisher MH, Weber AE. Naylor EM, et al. Among authors: wyvratt mj. Bioorg Med Chem Lett. 1998 Nov 3;8(21):3087-92. doi: 10.1016/s0960-894x(98)00571-x. Bioorg Med Chem Lett. 1998. PMID: 9873681
Human beta3 adrenergic receptor agonists containing cyclic ureidobenzenesulfonamides.
Parmee ER, Naylor EM, Perkins L, Colandrea VJ, Ok HO, Candelore MR, Cascieri MA, Deng L, Feeney WP, Forrest MJ, Hom GJ, MacIntyre DE, Miller RR, Stearns RA, Strader CD, Tota L, Wyvratt MJ, Fisher MH, Weber AE. Parmee ER, et al. Among authors: wyvratt mj. Bioorg Med Chem Lett. 1999 Mar 8;9(5):749-54. doi: 10.1016/s0960-894x(99)00073-6. Bioorg Med Chem Lett. 1999. PMID: 10201841
Human beta3 adrenergic receptor agonists containing imidazolidinone and imidazolone benzenesulfonamides.
Naylor EM, Parmee ER, Colandrea VJ, Perkins L, Brockunier L, Candelore MR, Cascieri MA, Colwell LF Jr, Deng L, Feeney WP, Forrest MJ, Hom GJ, MacIntyre DE, Strader CD, Tota L, Wang PR, Wyvratt MJ, Fisher MH, Weber AE. Naylor EM, et al. Among authors: wyvratt mj. Bioorg Med Chem Lett. 1999 Mar 8;9(5):755-8. doi: 10.1016/s0960-894x(99)00072-4. Bioorg Med Chem Lett. 1999. PMID: 10201842
L-770,644: a potent and selective human beta3 adrenergic receptor agonist with improved oral bioavailability.
Shih TL, Candelore MR, Cascieri MA, Chiu SH, Colwell LF Jr, Deng L, Feeney WP, Forrest MJ, Hom GJ, MacIntyre DE, Miller RR, Stearns RA, Strader CD, Tota L, Wyvratt MJ, Fisher MH, Weber AE. Shih TL, et al. Among authors: wyvratt mj. Bioorg Med Chem Lett. 1999 May 3;9(9):1251-4. doi: 10.1016/s0960-894x(99)00182-1. Bioorg Med Chem Lett. 1999. PMID: 10340609
Discovery of an orally bioavailable alkyl oxadiazole beta3 adrenergic receptor agonist.
Feng DD, Biftu T, Candelore MR, Cascieri MA, Colwell LF Jr, Deng L, Feeney WP, Forrest MJ, Hom GJ, MacIntyre DE, Miller RR, Stearns RA, Strader CD, Tota L, Wyvratt MJ, Fisher MH, Weber AE. Feng DD, et al. Among authors: wyvratt mj. Bioorg Med Chem Lett. 2000 Jul 3;10(13):1427-9. doi: 10.1016/s0960-894x(00)00267-5. Bioorg Med Chem Lett. 2000. PMID: 10888324
82 results