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Epigenetic remodeling in B-cell acute lymphoblastic leukemia occurs in two tracks and employs embryonic stem cell-like signatures.
Lee ST, Muench MO, Fomin ME, Xiao J, Zhou M, de Smith A, Martín-Subero JI, Heath S, Houseman EA, Roy R, Wrensch M, Wiencke J, Metayer C, Wiemels JL. Lee ST, et al. Among authors: xiao j. Nucleic Acids Res. 2015 Mar 11;43(5):2590-602. doi: 10.1093/nar/gkv103. Epub 2015 Feb 17. Nucleic Acids Res. 2015. PMID: 25690899 Free PMC article.
A global DNA methylation and gene expression analysis of early human B-cell development reveals a demethylation signature and transcription factor network.
Lee ST, Xiao Y, Muench MO, Xiao J, Fomin ME, Wiencke JK, Zheng S, Dou X, de Smith A, Chokkalingam A, Buffler P, Ma X, Wiemels JL. Lee ST, et al. Among authors: xiao y, xiao j. Nucleic Acids Res. 2012 Dec;40(22):11339-51. doi: 10.1093/nar/gks957. Epub 2012 Oct 16. Nucleic Acids Res. 2012. PMID: 23074194 Free PMC article.
A functional polymorphism in the CEBPE gene promoter influences acute lymphoblastic leukemia risk through interaction with the hematopoietic transcription factor Ikaros.
Wiemels JL, de Smith AJ, Xiao J, Lee ST, Muench MO, Fomin ME, Zhou M, Hansen HM, Termuhlen A, Metayer C, Walsh KM. Wiemels JL, et al. Among authors: xiao j. Leukemia. 2016 May;30(5):1194-7. doi: 10.1038/leu.2015.251. Epub 2015 Sep 16. Leukemia. 2016. PMID: 26437776 Free PMC article. No abstract available.
A Heritable Missense Polymorphism in CDKN2A Confers Strong Risk of Childhood Acute Lymphoblastic Leukemia and Is Preferentially Selected during Clonal Evolution.
Walsh KM, de Smith AJ, Hansen HM, Smirnov IV, Gonseth S, Endicott AA, Xiao J, Rice T, Fu CH, McCoy LS, Lachance DH, Eckel-Passow JE, Wiencke JK, Jenkins RB, Wrensch MR, Ma X, Metayer C, Wiemels JL. Walsh KM, et al. Among authors: xiao j. Cancer Res. 2015 Nov 15;75(22):4884-94. doi: 10.1158/0008-5472.CAN-15-1105. Epub 2015 Nov 2. Cancer Res. 2015. PMID: 26527286 Free PMC article.
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