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FXR-dependent Rubicon induction impairs autophagy in models of human cholestasis.
Panzitt K, Jungwirth E, Krones E, Lee JM, Pollheimer M, Thallinger GG, Kolb-Lenz D, Xiao R, Thorell A, Trauner M, Fickert P, Marschall HU, Moore DD, Wagner M. Panzitt K, et al. Among authors: xiao r. J Hepatol. 2020 Jun;72(6):1122-1131. doi: 10.1016/j.jhep.2020.01.014. Epub 2020 Jan 28. J Hepatol. 2020. PMID: 32001325 Free article.
International Union of Pharmacology. LXII. The NR1H and NR1I receptors: constitutive androstane receptor, pregnene X receptor, farnesoid X receptor alpha, farnesoid X receptor beta, liver X receptor alpha, liver X receptor beta, and vitamin D receptor.
Moore DD, Kato S, Xie W, Mangelsdorf DJ, Schmidt DR, Xiao R, Kliewer SA. Moore DD, et al. Among authors: xiao r. Pharmacol Rev. 2006 Dec;58(4):742-59. doi: 10.1124/pr.58.4.6. Pharmacol Rev. 2006. PMID: 17132852 Review.
Circadian dysregulation disrupts bile acid homeostasis.
Ma K, Xiao R, Tseng HT, Shan L, Fu L, Moore DD. Ma K, et al. Among authors: xiao r. PLoS One. 2009 Aug 31;4(8):e6843. doi: 10.1371/journal.pone.0006843. PLoS One. 2009. PMID: 19718444 Free PMC article.
Nutrient-sensing nuclear receptors coordinate autophagy.
Lee JM, Wagner M, Xiao R, Kim KH, Feng D, Lazar MA, Moore DD. Lee JM, et al. Among authors: xiao r. Nature. 2014 Dec 4;516(7529):112-5. doi: 10.1038/nature13961. Epub 2014 Nov 12. Nature. 2014. PMID: 25383539 Free PMC article.
Liver receptor homolog-1 is a critical determinant of methyl-pool metabolism.
Wagner M, Choi S, Panzitt K, Mamrosh JL, Lee JM, Zaufel A, Xiao R, Wooton-Kee R, Ståhlman M, Newgard CB, Borén J, Moore DD. Wagner M, et al. Among authors: xiao r. Hepatology. 2016 Jan;63(1):95-106. doi: 10.1002/hep.28124. Epub 2015 Oct 10. Hepatology. 2016. PMID: 26267291 Free PMC article.
Mutations in the nuclear bile acid receptor FXR cause progressive familial intrahepatic cholestasis.
Gomez-Ospina N, Potter CJ, Xiao R, Manickam K, Kim MS, Kim KH, Shneider BL, Picarsic JL, Jacobson TA, Zhang J, He W, Liu P, Knisely AS, Finegold MJ, Muzny DM, Boerwinkle E, Lupski JR, Plon SE, Gibbs RA, Eng CM, Yang Y, Washington GC, Porteus MH, Berquist WE, Kambham N, Singh RJ, Xia F, Enns GM, Moore DD. Gomez-Ospina N, et al. Among authors: xiao r. Nat Commun. 2016 Feb 18;7:10713. doi: 10.1038/ncomms10713. Nat Commun. 2016. PMID: 26888176 Free PMC article.
3,073 results