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ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease.
Lustbader JW, Cirilli M, Lin C, Xu HW, Takuma K, Wang N, Caspersen C, Chen X, Pollak S, Chaney M, Trinchese F, Liu S, Gunn-Moore F, Lue LF, Walker DG, Kuppusamy P, Zewier ZL, Arancio O, Stern D, Yan SS, Wu H. Lustbader JW, et al. Among authors: yan ss. Science. 2004 Apr 16;304(5669):448-52. doi: 10.1126/science.1091230. Science. 2004. PMID: 15087549
Inhibition of amyloid-beta (Abeta) peptide-binding alcohol dehydrogenase-Abeta interaction reduces Abeta accumulation and improves mitochondrial function in a mouse model of Alzheimer's disease.
Yao J, Du H, Yan S, Fang F, Wang C, Lue LF, Guo L, Chen D, Stern DM, Gunn Moore FJ, Xi Chen J, Arancio O, Yan SS. Yao J, et al. Among authors: yan ss, yan s. J Neurosci. 2011 Feb 9;31(6):2313-20. doi: 10.1523/JNEUROSCI.4717-10.2011. J Neurosci. 2011. PMID: 21307267 Free PMC article.
Synaptic mitochondrial pathology in Alzheimer's disease.
Du H, Guo L, Yan SS. Du H, et al. Among authors: yan ss. Antioxid Redox Signal. 2012 Jun 15;16(12):1467-75. doi: 10.1089/ars.2011.4277. Epub 2011 Dec 15. Antioxid Redox Signal. 2012. PMID: 21942330 Free PMC article. Review.
186 results