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Attenuation of colistin bactericidal activity by high inoculum of Pseudomonas aeruginosa characterized by a new mechanism-based population pharmacodynamic model.
Bulitta JB, Yang JC, Yohonn L, Ly NS, Brown SV, D'Hondt RE, Jusko WJ, Forrest A, Tsuji BT. Bulitta JB, et al. Among authors: yang jc. Antimicrob Agents Chemother. 2010 May;54(5):2051-62. doi: 10.1128/AAC.00881-09. Epub 2010 Mar 8. Antimicrob Agents Chemother. 2010. PMID: 20211900 Free PMC article.
A first-in-human, randomized, double-blind, placebo-controlled, single- and multiple-ascending oral dose study to assess the safety and tolerability of LFF571 in healthy volunteers.
Ting LS, Praestgaard J, Grunenberg N, Yang JC, Leeds JA, Pertel P. Ting LS, et al. Among authors: yang jc. Antimicrob Agents Chemother. 2012 Nov;56(11):5946-51. doi: 10.1128/AAC.00867-12. Epub 2012 Sep 10. Antimicrob Agents Chemother. 2012. PMID: 22964250 Free PMC article. Clinical Trial.
Optimizing use of quinolones in the critically ill.
Yang JC, Tsuji BT, Forrest A. Yang JC, et al. Semin Respir Crit Care Med. 2007 Dec;28(6):586-95. doi: 10.1055/s-2007-996405. Semin Respir Crit Care Med. 2007. PMID: 18095222 Review.
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