Yang XF - Search Results

1

Collapsin response mediator protein 2 (CRMP2) interacts with N-methyl-D-aspartate (NMDA) receptor and Na+/Ca2+ exchanger and regulates their functional activity.

Brustovetsky T, Pellman JJ, Yang XF, Khanna R, Brustovetsky N. Brustovetsky T, et al. Among authors: yang xf. J Biol Chem. 2014 Mar 14;289(11):7470-82. doi: 10.1074/jbc.M113.518472. Epub 2014 Jan 28. J Biol Chem. 2014. PMID: 24474686 Free PMC article.

2

Hierarchical CRMP2 posttranslational modifications control NaV1.7 function.

Dustrude ET, Moutal A, Yang X, Wang Y, Khanna M, Khanna R. Dustrude ET, et al. Proc Natl Acad Sci U S A. 2016 Dec 27;113(52):E8443-E8452. doi: 10.1073/pnas.1610531113. Epub 2016 Dec 8. Proc Natl Acad Sci U S A. 2016. PMID: 27940916 Free PMC article.

3

A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses inflammatory and postoperative pain behaviors.

François-Moutal L, Wang Y, Moutal A, Cottier KE, Melemedjian OK, Yang X, Wang Y, Ju W, Largent-Milnes TM, Khanna M, Vanderah TW, Khanna R. François-Moutal L, et al. Pain. 2015 Jul;156(7):1247-1264. doi: 10.1097/j.pain.0000000000000147. Pain. 2015. PMID: 25782368 Free PMC article.

4

Sustained relief of ongoing experimental neuropathic pain by a CRMP2 peptide aptamer with low abuse potential.

Xie JY, Chew LA, Yang X, Wang Y, Qu C, Wang Y, Federici LM, Fitz SD, Ripsch MS, Due MR, Moutal A, Khanna M, White FA, Vanderah TW, Johnson PL, Porreca F, Khanna R. Xie JY, et al. Pain. 2016 Sep;157(9):2124-2140. doi: 10.1097/j.pain.0000000000000628. Pain. 2016. PMID: 27537210 Free PMC article.

5

CRISPR/Cas9 editing of Nf1 gene identifies CRMP2 as a therapeutic target in neurofibromatosis type 1-related pain that is reversed by (S)-Lacosamide.

Moutal A, Yang X, Li W, Gilbraith KB, Luo S, Cai S, François-Moutal L, Chew LA, Yeon SK, Bellampalli SS, Qu C, Xie JY, Ibrahim MM, Khanna M, Park KD, Porreca F, Khanna R. Moutal A, et al. Pain. 2017 Dec;158(12):2301-2319. doi: 10.1097/j.pain.0000000000001002. Pain. 2017. PMID: 28809766 Free PMC article.

6

Differential regulation of collapsin response mediator protein 2 (CRMP2) phosphorylation by GSK3ß and CDK5 following traumatic brain injury.

Wilson SM, Ki Yeon S, Yang XF, Park KD, Khanna R. Wilson SM, et al. Among authors: yang xf. Front Cell Neurosci. 2014 May 28;8:135. doi: 10.3389/fncel.2014.00135. eCollection 2014. Front Cell Neurosci. 2014. PMID: 24904280 Free PMC article.

7

(S)-lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation pharmacology.

Moutal A, Chew LA, Yang X, Wang Y, Yeon SK, Telemi E, Meroueh S, Park KD, Shrinivasan R, Gilbraith KB, Qu C, Xie JY, Patwardhan A, Vanderah TW, Khanna M, Porreca F, Khanna R. Moutal A, et al. Pain. 2016 Jul;157(7):1448-1463. doi: 10.1097/j.pain.0000000000000555. Pain. 2016. PMID: 26967696 Free PMC article.

8

Dissecting the role of the CRMP2-neurofibromin complex on pain behaviors.

Moutal A, Wang Y, Yang X, Ji Y, Luo S, Dorame A, Bellampalli SS, Chew LA, Cai S, Dustrude ET, Keener JE, Marty MT, Vanderah TW, Khanna R. Moutal A, et al. Pain. 2017 Nov;158(11):2203-2221. doi: 10.1097/j.pain.0000000000001026. Pain. 2017. PMID: 28767512 Free PMC article.

9

CRMP2-Neurofibromin Interface Drives NF1-related Pain.

Moutal A, Sun L, Yang X, Li W, Cai S, Luo S, Khanna R. Moutal A, et al. Neuroscience. 2018 Jun 15;381:79-90. doi: 10.1016/j.neuroscience.2018.04.002. Epub 2018 Apr 12. Neuroscience. 2018. PMID: 29655575 Free PMC article.

10

Discovery of lacosamide affinity bait agents that exhibit potent voltage-gated sodium channel blocking properties.

Park KD, Yang XF, Lee H, Dustrude ET, Wang Y, Khanna R, Kohn H. Park KD, et al. Among authors: yang xf. ACS Chem Neurosci. 2013 Mar 20;4(3):463-74. doi: 10.1021/cn300188h. Epub 2013 Jan 16. ACS Chem Neurosci. 2013. PMID: 23509982 Free PMC article.

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