You QD - Search Results

1

HIF-1α is critical for hypoxia-mediated maintenance of glioblastoma stem cells by activating Notch signaling pathway.

Qiang L, Wu T, Zhang HW, Lu N, Hu R, Wang YJ, Zhao L, Chen FH, Wang XT, You QD, Guo QL. Qiang L, et al. Among authors: you qd. Cell Death Differ. 2012 Feb;19(2):284-94. doi: 10.1038/cdd.2011.95. Epub 2011 Aug 5. Cell Death Differ. 2012. PMID: 21818118 Free PMC article.

2

NF-κB and Nrf2 signaling pathways contribute to wogonin-mediated inhibition of inflammation-associated colorectal carcinogenesis.

Yao J, Zhao L, Zhao Q, Zhao Y, Sun Y, Zhang Y, Miao H, You QD, Hu R, Guo QL. Yao J, et al. Among authors: you qd. Cell Death Dis. 2014 Jun 5;5(6):e1283. doi: 10.1038/cddis.2014.221. Cell Death Dis. 2014. PMID: 24901054 Free PMC article.

3

Recent progress of small molecular VEGFR inhibitors as anticancer agents.

Xu D, Wang TL, Sun LP, You QD. Xu D, et al. Among authors: you qd. Mini Rev Med Chem. 2011 Jan;11(1):18-31. doi: 10.2174/138955711793564015. Mini Rev Med Chem. 2011. PMID: 21034401 Review.

4

Discovery of Pyrazolo[1,5-a]pyrimidine Derivative as a Novel and Selective ALKBH5 Inhibitor for the Treatment of AML.

Wang YZ, Li HY, Zhang Y, Jiang RX, Xu J, Gu J, Jiang Z, Jiang ZY, You QD, Guo XK. Wang YZ, et al. Among authors: you qd. J Med Chem. 2023 Dec 14;66(23):15944-15959. doi: 10.1021/acs.jmedchem.3c01374. Epub 2023 Nov 20. J Med Chem. 2023. PMID: 37983486

5

Inhibitors of Stimulator of Interferon Genes from 2019 to July 2022: An Overview of the Structure and Bioactivity.

Xu F, Tian X, Zhu Q, Feng Z, Li H, Dai W, Zhou Y, You QD, Xu X. Xu F, et al. Among authors: you qd. Curr Drug Targets. 2023;24(12):959-980. doi: 10.2174/1389450124666230831160820. Curr Drug Targets. 2023. PMID: 37653633

6

Development of Orally Bioavailable Amidobenzimidazole Analogues Targeting Stimulator of Interferon Gene (STING) Receptor.

Chen NN, Zhang H, Zhu QS, Zeng T, Dai W, Zhou YL, Xin GF, Wu BD, Gong SJ, Jiang ZY, You QD, Xu XL. Chen NN, et al. Among authors: you qd. J Med Chem. 2023 Apr 27;66(8):5584-5610. doi: 10.1021/acs.jmedchem.2c02046. Epub 2023 Apr 7. J Med Chem. 2023. PMID: 37027512

7

Imidazo[1,2-a]Pyridine Derivatives as Novel Dual-Target Inhibitors of ABCB1 and ABCG2 for Reversing Multidrug Resistance.

Li H, Zhang SL, Jia YH, Li Q, Feng ZW, Zhang SD, Zheng W, Zhou YL, Li LL, Liu XC, Chen YQ, Peng H, You QD, Xu XL. Li H, et al. Among authors: you qd. J Med Chem. 2023 Feb 23;66(4):2804-2831. doi: 10.1021/acs.jmedchem.2c01862. Epub 2023 Feb 13. J Med Chem. 2023. PMID: 36780419

8

Medicinal chemistry perspective on cGAS-STING signaling pathway with small molecule inhibitors.

Tian X, Xu F, Zhu Q, Feng Z, Dai W, Zhou Y, You QD, Xu X. Tian X, et al. Among authors: you qd. Eur J Med Chem. 2022 Dec 15;244:114791. doi: 10.1016/j.ejmech.2022.114791. Epub 2022 Sep 24. Eur J Med Chem. 2022. PMID: 36206657 Review.

9

Discovery of 2-((2-methylbenzyl)thio)-6-oxo-4-(3,4,5-trimethoxyphenyl)-1,6-dihydropyrimidine-5-carbonitrile as a novel and effective bromodomain and extra-terminal (BET) inhibitor for the treatment of sepsis.

Chen X, Meng F, Zhang J, Zhang Z, Ye X, Zhang W, Tong Y, Ji X, Xu R, Xu XL, You QD, Jiang ZY. Chen X, et al. Among authors: you qd. Eur J Med Chem. 2022 Aug 5;238:114423. doi: 10.1016/j.ejmech.2022.114423. Epub 2022 May 8. Eur J Med Chem. 2022. PMID: 35544982

10

Target Fishing Reveals a Novel Mechanism of 1,2,4-Oxadiazole Derivatives Targeting Rpn6, a Subunit of 26S Proteasome.

Dai Z, An LY, Chen XY, Yang F, Zhao N, Li CC, Ren R, Li BY, Tao WY, Li P, Jiang C, Yan F, Jiang ZY, You QD, Di B, Xu LL. Dai Z, et al. Among authors: you qd. J Med Chem. 2022 Mar 24;65(6):5029-5043. doi: 10.1021/acs.jmedchem.1c02210. Epub 2022 Mar 6. J Med Chem. 2022. PMID: 35253427

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