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Exome-wide association study of plasma lipids in >300,000 individuals.
Liu DJ, Peloso GM, Yu H, Butterworth AS, Wang X, Mahajan A, Saleheen D, Emdin C, Alam D, Alves AC, Amouyel P, Di Angelantonio E, Arveiler D, Assimes TL, Auer PL, Baber U, Ballantyne CM, Bang LE, Benn M, Bis JC, Boehnke M, Boerwinkle E, Bork-Jensen J, Bottinger EP, Brandslund I, Brown M, Busonero F, Caulfield MJ, Chambers JC, Chasman DI, Chen YE, Chen YI, Chowdhury R, Christensen C, Chu AY, Connell JM, Cucca F, Cupples LA, Damrauer SM, Davies G, Deary IJ, Dedoussis G, Denny JC, Dominiczak A, Dubé MP, Ebeling T, Eiriksdottir G, Esko T, Farmaki AE, Feitosa MF, Ferrario M, Ferrieres J, Ford I, Fornage M, Franks PW, Frayling TM, Frikke-Schmidt R, Fritsche LG, Frossard P, Fuster V, Ganesh SK, Gao W, Garcia ME, Gieger C, Giulianini F, Goodarzi MO, Grallert H, Grarup N, Groop L, Grove ML, Gudnason V, Hansen T, Harris TB, Hayward C, Hirschhorn JN, Holmen OL, Huffman J, Huo Y, Hveem K, Jabeen S, Jackson AU, Jakobsdottir J, Jarvelin MR, Jensen GB, Jørgensen ME, Jukema JW, Justesen JM, Kamstrup PR, Kanoni S, Karpe F, Kee F, Khera AV, Klarin D, Koistinen HA, Kooner JS, Kooperberg C, Kuulasmaa K, Kuusisto J, Laakso M, Lakka T, Langenberg C, Langsted A, Launer LJ, Lauritzen T, Liewald DCM… See abstract for full author list ➔ Liu DJ, et al. Among authors: yu h. Nat Genet. 2017 Dec;49(12):1758-1766. doi: 10.1038/ng.3977. Epub 2017 Oct 30. Nat Genet. 2017. PMID: 29083408 Free PMC article.
GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis.
Yu H, Rimbert A, Palmer AE, Toyohara T, Xia Y, Xia F, Ferreira LMR, Chen Z, Chen T, Loaiza N, Horwitz NB, Kacergis MC, Zhao L; BIOS Consortium; Soukas AA, Kuivenhoven JA, Kathiresan S, Cowan CA. Yu H, et al. Cell. 2019 Nov 27;179(6):1276-1288.e14. doi: 10.1016/j.cell.2019.10.034. Cell. 2019. PMID: 31778654 Free PMC article.
The FES Gene at the 15q26 Coronary-Artery-Disease Locus Inhibits Atherosclerosis.
Karamanavi E, McVey DG, van der Laan SW, Stanczyk PJ, Morris GE, Wang Y, Yang W, Chan K, Poston RN, Luo J, Zhou X, Gong P, Jones PD, Cao J, Kostogrys RB, Webb TR, Pasterkamp G, Yu H, Xiao Q, Greer PA, Stringer EJ, Samani NJ, Ye S. Karamanavi E, et al. Among authors: yu h. Circ Res. 2022 Dec 2;131(12):1004-1017. doi: 10.1161/CIRCRESAHA.122.321146. Epub 2022 Nov 2. Circ Res. 2022. PMID: 36321446 Free PMC article.
Chromatin regulator SMARCAL1 modulates cellular lipid metabolism.
Nagai TH, Hartigan C, Mizoguchi T, Yu H, Deik A, Bullock K, Wang Y, Cromley D, Schenone M, Cowan CA, Rader DJ, Clish CB, Carr SA, Xu YX. Nagai TH, et al. Among authors: yu h. Commun Biol. 2023 Dec 21;6(1):1298. doi: 10.1038/s42003-023-05665-6. Commun Biol. 2023. PMID: 38129665 Free PMC article.
Mitoregulin Controls β-Oxidation in Human and Mouse Adipocytes.
Friesen M, Warren CR, Yu H, Toyohara T, Ding Q, Florido MHC, Sayre C, Pope BD, Goff LA, Rinn JL, Cowan CA. Friesen M, et al. Among authors: yu h. Stem Cell Reports. 2020 Apr 14;14(4):590-602. doi: 10.1016/j.stemcr.2020.03.002. Epub 2020 Apr 2. Stem Cell Reports. 2020. PMID: 32243843 Free PMC article.
Patient hiPSCs Identify Vascular Smooth Muscle Arylacetamide Deacetylase as Protective against Atherosclerosis.
Toyohara T, Roudnicky F, Florido MHC, Nakano T, Yu H, Katsuki S, Lee M, Meissner T, Friesen M, Davidow LS, Ptaszek L, Abe T, Rubin LL, Pereira AC, Aikawa M, Cowan CA. Toyohara T, et al. Among authors: yu h. Cell Stem Cell. 2020 Jul 2;27(1):147-157.e7. doi: 10.1016/j.stem.2020.04.018. Epub 2020 May 14. Cell Stem Cell. 2020. PMID: 32413331 Free PMC article.
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