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Loss of Asxl1 leads to myelodysplastic syndrome-like disease in mice.
Wang J, Li Z, He Y, Pan F, Chen S, Rhodes S, Nguyen L, Yuan J, Jiang L, Yang X, Weeks O, Liu Z, Zhou J, Ni H, Cai CL, Xu M, Yang FC. Wang J, et al. Among authors: yuan j. Blood. 2014 Jan 23;123(4):541-53. doi: 10.1182/blood-2013-05-500272. Epub 2013 Nov 19. Blood. 2014. PMID: 24255920 Free PMC article.
An abnormal bone marrow microenvironment contributes to hematopoietic dysfunction in Fanconi anemia.
Zhou Y, He Y, Xing W, Zhang P, Shi H, Chen S, Shi J, Bai J, Rhodes SD, Zhang F, Yuan J, Yang X, Zhu X, Li Y, Hanenberg H, Xu M, Robertson KA, Yuan W, Nalepa G, Cheng T, Clapp DW, Yang FC. Zhou Y, et al. Among authors: yuan w, yuan j. Haematologica. 2017 Jun;102(6):1017-1027. doi: 10.3324/haematol.2016.158717. Epub 2017 Mar 24. Haematologica. 2017. PMID: 28341737 Free PMC article.
Early administration of imatinib mesylate reduces plexiform neurofibroma tumor burden with durable results after drug discontinuation in a mouse model of neurofibromatosis type 1.
Armstrong AE, Rhodes SD, Smith A, Chen S, Bessler W, Ferguson MJ, Jiang L, Li X, Yuan J, Yang X, Yang FC, Robertson KA, Ingram DA, Blakeley JO, Clapp DW. Armstrong AE, et al. Among authors: yuan j. Pediatr Blood Cancer. 2020 Aug;67(8):e28372. doi: 10.1002/pbc.28372. Epub 2020 May 27. Pediatr Blood Cancer. 2020. PMID: 32459399 Free PMC article.
Ex vivo culture of Fancc-/- stem/progenitor cells predisposes cells to undergo apoptosis, and surviving stem/progenitor cells display cytogenetic abnormalities and an increased risk of malignancy.
Li X, Le Beau MM, Ciccone S, Yang FC, Freie B, Chen S, Yuan J, Hong P, Orazi A, Haneline LS, Clapp DW. Li X, et al. Among authors: yuan j. Blood. 2005 May 1;105(9):3465-71. doi: 10.1182/blood-2004-06-2483. Epub 2005 Jan 11. Blood. 2005. PMID: 15644418 Free PMC article.
14,833 results
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