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Page 1
A humanized nanobody phage display library yields potent binders of SARS CoV-2 spike.
Fu Y, da Fonseca Rezende E Mello J, Fleming BD, Renn A, Chen CZ, Hu X, Xu M, Gorshkov K, Hanson Q, Zheng W, Lee EM, Perera L, Petrovich R, Pradhan M, Eastman RT, Itkin Z, Stanley TB, Hsu A, Dandey V, Sharma K, Gillette W, Taylor T, Ramakrishnan N, Perkins S, Esposito D, Oh E, Susumu K, Wolak M, Ferrer M, Hall MD, Borgnia MJ, Simeonov A. Fu Y, et al. PLoS One. 2022 Aug 10;17(8):e0272364. doi: 10.1371/journal.pone.0272364. eCollection 2022. PLoS One. 2022. PMID: 35947606 Free PMC article.
A new class of cytotoxic agents targets tubulin and disrupts microtubule dynamics.
Al-Hamashi AA, Koranne R, Dlamini S, Alqahtani A, Karaj E, Rashid MS, Knoff JR, Dunworth M, Pflum MKH, Casero RA Jr, Perera L, Taylor WR, Tillekeratne LMV. Al-Hamashi AA, et al. Bioorg Chem. 2021 Nov;116:105297. doi: 10.1016/j.bioorg.2021.105297. Epub 2021 Aug 30. Bioorg Chem. 2021. PMID: 34509798 Free PMC article.
Characterization of SARS2 Nsp15 nuclease activity reveals it's mad about U.
Frazier MN, Dillard LB, Krahn JM, Perera L, Williams JG, Wilson IM, Stewart ZD, Pillon MC, Deterding LJ, Borgnia MJ, Stanley RE. Frazier MN, et al. Nucleic Acids Res. 2021 Sep 27;49(17):10136-10149. doi: 10.1093/nar/gkab719. Nucleic Acids Res. 2021. PMID: 34403466 Free PMC article.
28 results