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Monensin inhibits canonical Wnt signaling in human colorectal cancer cells and suppresses tumor growth in multiple intestinal neoplasia mice.
Tumova L, Pombinho AR, Vojtechova M, Stancikova J, Gradl D, Krausova M, Sloncova E, Horazna M, Kriz V, Machonova O, Jindrich J, Zdrahal Z, Bartunek P, Korinek V. Tumova L, et al. Among authors: zdrahal z. Mol Cancer Ther. 2014 Apr;13(4):812-22. doi: 10.1158/1535-7163.MCT-13-0625. Epub 2014 Feb 19. Mol Cancer Ther. 2014. PMID: 24552772
RNF43 truncations trap CK1 to drive niche-independent self-renewal in cancer.
Spit M, Fenderico N, Jordens I, Radaszkiewicz T, Lindeboom RG, Bugter JM, Cristobal A, Ootes L, van Osch M, Janssen E, Boonekamp KE, Hanakova K, Potesil D, Zdrahal Z, Boj SF, Medema JP, Bryja V, Koo BK, Vermeulen M, Maurice MM. Spit M, et al. Among authors: zdrahal z. EMBO J. 2020 Sep 15;39(18):e103932. doi: 10.15252/embj.2019103932. Epub 2020 Aug 10. EMBO J. 2020. PMID: 32965059 Free PMC article.
RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.
Radaszkiewicz T, Nosková M, Gömöryová K, Vondálová Blanářová O, Radaszkiewicz KA, Picková M, Víchová R, Gybeľ T, Kaiser K, Demková L, Kučerová L, Bárta T, Potěšil D, Zdráhal Z, Souček K, Bryja V. Radaszkiewicz T, et al. Among authors: zdrahal z. Elife. 2021 Oct 27;10:e65759. doi: 10.7554/eLife.65759. Elife. 2021. PMID: 34702444 Free PMC article.
Toll-Like Receptor 3 Overexpression Induces Invasion of Prostate Cancer Cells, whereas Its Activation Triggers Apoptosis.
Muresan XM, Slabáková E, Procházková J, Drápela S, Fedr R, Pícková M, Vacek O, Víchová R, Suchánková T, Bouchal J, Kürfürstová D, Král M, Hulínová T, Sýkora RP, Študent V, Hejret V, van Weerden WM, Puhr M, Pustka V, Potěšil D, Zdráhal Z, Culig Z, Souček K. Muresan XM, et al. Among authors: zdrahal z. Am J Pathol. 2022 Sep;192(9):1321-1335. doi: 10.1016/j.ajpath.2022.05.009. Epub 2022 Jun 22. Am J Pathol. 2022. PMID: 35750257 Free article.
Proteomic analysis in multiple myeloma research.
Cumova J, Potacova A, Zdrahal Z, Hajek R. Cumova J, et al. Among authors: zdrahal z. Mol Biotechnol. 2011 Jan;47(1):83-93. doi: 10.1007/s12033-010-9326-x. Mol Biotechnol. 2011. PMID: 20730509 Review.
A combined approach for the study of histone deacetylase inhibitors.
Činčárová L, Lochmanová G, Nováková K, Šultesová P, Konečná H, Fajkusová L, Fajkus J, Zdráhal Z. Činčárová L, et al. Among authors: zdrahal z. Mol Biosyst. 2012 Nov;8(11):2937-45. doi: 10.1039/c2mb25136a. Mol Biosyst. 2012. PMID: 22915142
195 results