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Page 1
A Loss-of-Function Splice Acceptor Variant in IGF2 Is Protective for Type 2 Diabetes.
Mercader JM, Liao RG, Bell AD, Dymek Z, Estrada K, Tukiainen T, Huerta-Chagoya A, Moreno-Macías H, Jablonski KA, Hanson RL, Walford GA, Moran I, Chen L, Agarwala V, Ordoñez-Sánchez ML, Rodríguez-Guillen R, Rodríguez-Torres M, Segura-Kato Y, García-Ortiz H, Centeno-Cruz F, Barajas-Olmos F, Caulkins L, Puppala S, Fontanillas P, Williams AL, Bonàs-Guarch S, Hartl C, Ripke S; Diabetes Prevention Program Research Group; Tooley K, Lane J, Zerrweck C, Martínez-Hernández A, Córdova EJ, Mendoza-Caamal E, Contreras-Cubas C, González-Villalpando ME, Cruz-Bautista I, Muñoz-Hernández L, Gómez-Velasco D, Alvirde U, Henderson BE, Wilkens LR, Le Marchand L, Arellano-Campos O, Riba L, Harden M; Broad Genomics Platform; Gabriel S; T2D-GENES Consortium; Abboud HE, Cortes ML, Revilla-Monsalve C, Islas-Andrade S, Soberon X, Curran JE, Jenkinson CP, DeFronzo RA, Lehman DM, Hanis CL, Bell GI, Boehnke M, Blangero J, Duggirala R, Saxena R, MacArthur D, Ferrer J, McCarroll SA, Torrents D, Knowler WC, Baier LJ, Burtt N, González-Villalpando C, Haiman CA, Aguilar-Salinas CA, Tusié-Luna T, Flannick J, Jacobs SBR, Orozco L, Altshuler D, Florez JC; SIGMA T2D Genetics Consortium. Mercader JM, et al. Among authors: zerrweck c. Diabetes. 2017 Nov;66(11):2903-2914. doi: 10.2337/db17-0187. Epub 2017 Aug 24. Diabetes. 2017. PMID: 28838971 Free PMC article.
Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms.
Rusu V, Hoch E, Mercader JM, Tenen DE, Gymrek M, Hartigan CR, DeRan M, von Grotthuss M, Fontanillas P, Spooner A, Guzman G, Deik AA, Pierce KA, Dennis C, Clish CB, Carr SA, Wagner BK, Schenone M, Ng MCY, Chen BH; MEDIA Consortium; SIGMA T2D Consortium; Centeno-Cruz F, Zerrweck C, Orozco L, Altshuler DM, Schreiber SL, Florez JC, Jacobs SBR, Lander ES. Rusu V, et al. Among authors: zerrweck c. Cell. 2017 Jun 29;170(1):199-212.e20. doi: 10.1016/j.cell.2017.06.011. Cell. 2017. PMID: 28666119 Free PMC article.
Altered DNA methylation in liver and adipose tissues derived from individuals with obesity and type 2 diabetes.
Barajas-Olmos F, Centeno-Cruz F, Zerrweck C, Imaz-Rosshandler I, Martínez-Hernández A, Cordova EJ, Rangel-Escareño C, Gálvez F, Castillo A, Maydón H, Campos F, Maldonado-Pintado DG, Orozco L. Barajas-Olmos F, et al. Among authors: zerrweck c. BMC Med Genet. 2018 Feb 21;19(1):28. doi: 10.1186/s12881-018-0542-8. BMC Med Genet. 2018. PMID: 29466957 Free PMC article.
Two novel variants in DYRK1B causative of AOMS3: expanding the clinical spectrum.
Mendoza-Caamal EC, Barajas-Olmos F, Mirzaeicheshmeh E, Ilizaliturri-Flores I, Aguilar-Salinas CA, Gómez-Velasco DV, Cicerón-Arellano I, Reséndiz-Rodríguez A, Martínez-Hernández A, Contreras-Cubas C, Islas-Andrade S, Zerrweck C, García-Ortiz H, Orozco L. Mendoza-Caamal EC, et al. Among authors: zerrweck c. Orphanet J Rare Dis. 2021 Jun 30;16(1):291. doi: 10.1186/s13023-021-01924-z. Orphanet J Rare Dis. 2021. PMID: 34193236 Free PMC article.
Alterations of DNA methylation during adipogenesis differentiation of mesenchymal stem cells isolated from adipose tissue of patients with obesity is associated with type 2 diabetes.
Mirzaeicheshmeh E, Zerrweck C, Centeno-Cruz F, Baca-Peynado P, Martinez-Hernandez A, García-Ortiz H, Contreras-Cubas C, Salas-Martínez MG, Saldaña-Alvarez Y, Mendoza-Caamal EC, Barajas-Olmos F, Orozco L. Mirzaeicheshmeh E, et al. Among authors: zerrweck c. Adipocyte. 2021 Dec;10(1):493-504. doi: 10.1080/21623945.2021.1978157. Adipocyte. 2021. PMID: 34699309 Free PMC article.
DNA methylation and gene expression analysis in adipose tissue to identify new loci associated with T2D development in obesity.
Baca P, Barajas-Olmos F, Mirzaeicheshmeh E, Zerrweck C, Guilbert L, Sánchez EC, Flores-Huacuja M, Villafán R, Martínez-Hernández A, García-Ortiz H, Contreras-Cubas C, Centeno-Cruz F, Orozco L. Baca P, et al. Among authors: zerrweck c. Nutr Diabetes. 2022 Dec 19;12(1):50. doi: 10.1038/s41387-022-00228-w. Nutr Diabetes. 2022. PMID: 36535927 Free PMC article.
Effect of the Melanocortin 4-Receptor Ile269Asn Mutation on Weight Loss Response to Dietary, Phentermine and Bariatric Surgery Interventions.
Salazar-Valencia IG, Villamil-Ramírez H, Barajas-Olmos F, Guevara-Cruz M, Macias-Kauffer LR, García-Ortiz H, Hernández-Vergara O, Díaz de Sandy-Galán DA, León-Mimila P, Centeno-Cruz F, González-Salazar LE, Guizar-Heredia R, Pichardo-Ontiveros E, Jacobo-Albavera L, Posadas-Sánchez R, Vargas-Alarcón G, Velazquez-Cruz R, Gutiérrez-Aguilar R, Zerrweck C, Rocha-González HI, Reyes-García JG, Carrasco-Portugal MDC, Flores-Murrieta FJ, Tovar AR, Orozco L, Villarreal-Molina T, Canizales-Quinteros S. Salazar-Valencia IG, et al. Among authors: zerrweck c. Genes (Basel). 2022 Dec 1;13(12):2267. doi: 10.3390/genes13122267. Genes (Basel). 2022. PMID: 36553534 Free PMC article.
55 results