Evaluation of an improved branch-site likelihood method for detecting positive selection at the molecular level.
Zhang J, Nielsen R, Yang Z.
Zhang J, et al.
Mol Biol Evol. 2005 Dec;22(12):2472-9. doi: 10.1093/molbev/msi237. Epub 2005 Aug 17.
Mol Biol Evol. 2005.
PMID: 16107592
However, computer simulations suggested that the tests were sensitive to the model assumptions and were unable to distinguish between relaxation of selective constraint and positive selection (Zhang, J. 2004. Frequent false detection of positive selection by the lik …
However, computer simulations suggested that the tests were sensitive to the model assumptions and were unable to distinguish between relaxa …