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Multistage genome-wide association meta-analyses identified two new loci for bone mineral density.
Zhang L, Choi HJ, Estrada K, Leo PJ, Li J, Pei YF, Zhang Y, Lin Y, Shen H, Liu YZ, Liu Y, Zhao Y, Zhang JG, Tian Q, Wang YP, Han Y, Ran S, Hai R, Zhu XZ, Wu S, Yan H, Liu X, Yang TL, Guo Y, Zhang F, Guo YF, Chen Y, Chen X, Tan L, Zhang L, Deng FY, Deng H, Rivadeneira F, Duncan EL, Lee JY, Han BG, Cho NH, Nicholson GC, McCloskey E, Eastell R, Prince RL, Eisman JA, Jones G, Reid IR, Sambrook PN, Dennison EM, Danoy P, Yerges-Armstrong LM, Streeten EA, Hu T, Xiang S, Papasian CJ, Brown MA, Shin CS, Uitterlinden AG, Deng HW. Zhang L, et al. Among authors: zhang f, zhang jg, zhang y. Hum Mol Genet. 2014 Apr 1;23(7):1923-33. doi: 10.1093/hmg/ddt575. Epub 2013 Nov 17. Hum Mol Genet. 2014. PMID: 24249740 Free PMC article.
Impaired osteoblast function in GPRC6A null mice.
Pi M, Zhang L, Lei SF, Huang MZ, Zhu W, Zhang J, Shen H, Deng HW, Quarles LD. Pi M, et al. Among authors: zhang l, zhang j. J Bone Miner Res. 2010 May;25(5):1092-102. doi: 10.1359/jbmr.091037. J Bone Miner Res. 2010. PMID: 19874200 Free PMC article.
HMGA2 is confirmed to be associated with human adult height.
Yang TL, Guo Y, Zhang LS, Tian Q, Yan H, Guo YF, Deng HW. Yang TL, et al. Ann Hum Genet. 2010 Jan;74(1):11-6. doi: 10.1111/j.1469-1809.2009.00555.x. Epub 2009 Nov 20. Ann Hum Genet. 2010. PMID: 19930247 Free PMC article.
Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis.
Guo Y, Tan LJ, Lei SF, Yang TL, Chen XD, Zhang F, Chen Y, Pan F, Yan H, Liu X, Tian Q, Zhang ZX, Zhou Q, Qiu C, Dong SS, Xu XH, Guo YF, Zhu XZ, Liu SL, Wang XL, Li X, Luo Y, Zhang LS, Li M, Wang JT, Wen T, Drees B, Hamilton J, Papasian CJ, Recker RR, Song XP, Cheng J, Deng HW. Guo Y, et al. PLoS Genet. 2010 Jan 8;6(1):e1000806. doi: 10.1371/journal.pgen.1000806. PLoS Genet. 2010. PMID: 20072603 Free PMC article.
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