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Airway smooth muscle STIM1 and Orai1 are upregulated in asthmatic mice and mediate PDGF-activated SOCE, CRAC currents, proliferation, and migration.
Spinelli AM, González-Cobos JC, Zhang X, Motiani RK, Rowan S, Zhang W, Garrett J, Vincent PA, Matrougui K, Singer HA, Trebak M. Spinelli AM, et al. Among authors: zhang w, zhang x. Pflugers Arch. 2012 Nov;464(5):481-92. doi: 10.1007/s00424-012-1160-5. Epub 2012 Sep 27. Pflugers Arch. 2012. PMID: 23014880 Free PMC article.
Essential Role of Smooth Muscle STIM1 in Hypertension and Cardiovascular Dysfunction.
Kassan M, Ait-Aissa K, Radwan E, Mali V, Haddox S, Gabani M, Zhang W, Belmadani S, Irani K, Trebak M, Matrougui K. Kassan M, et al. Among authors: zhang w. Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1900-9. doi: 10.1161/ATVBAHA.116.307869. Epub 2016 Jul 28. Arterioscler Thromb Vasc Biol. 2016. PMID: 27470514 Free PMC article.
STIM1 and Orai1: novel targets for vascular diseases?
Zhang W, Trebak M. Zhang W, et al. Sci China Life Sci. 2011 Aug;54(8):780-5. doi: 10.1007/s11427-011-4206-6. Epub 2011 Jul 24. Sci China Life Sci. 2011. PMID: 21786201 Free PMC article. Review.
Orai1-mediated I (CRAC) is essential for neointima formation after vascular injury.
Zhang W, Halligan KE, Zhang X, Bisaillon JM, Gonzalez-Cobos JC, Motiani RK, Hu G, Vincent PA, Zhou J, Barroso M, Singer HA, Matrougui K, Trebak M. Zhang W, et al. Among authors: zhang x. Circ Res. 2011 Aug 19;109(5):534-42. doi: 10.1161/CIRCRESAHA.111.246777. Epub 2011 Jul 7. Circ Res. 2011. PMID: 21737791 Free PMC article.
What role for store-operated Ca²⁺ entry in muscle?
Trebak M, Zhang W, Ruhle B, Henkel MM, González-Cobos JC, Motiani RK, Stolwijk JA, Newton RL, Zhang X. Trebak M, et al. Among authors: zhang w, zhang x. Microcirculation. 2013 May;20(4):330-6. doi: 10.1111/micc.12042. Microcirculation. 2013. PMID: 23312019 Free PMC article. Review.
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