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De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population.
Kessler MD, Loesch DP, Perry JA, Heard-Costa NL, Taliun D, Cade BE, Wang H, Daya M, Ziniti J, Datta S, Celedón JC, Soto-Quiros ME, Avila L, Weiss ST, Barnes K, Redline SS, Vasan RS, Johnson AD, Mathias RA, Hernandez R, Wilson JG, Nickerson DA, Abecasis G, Browning SR, Zöllner S, O'Connell JR, Mitchell BD; National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Consortium; TOPMed Population Genetics Working Group; O'Connor TD. Kessler MD, et al. Proc Natl Acad Sci U S A. 2020 Feb 4;117(5):2560-2569. doi: 10.1073/pnas.1902766117. Epub 2020 Jan 21. Proc Natl Acad Sci U S A. 2020. PMID: 31964835 Free PMC article.
Lifestyle Risk Score: handling missingness of individual lifestyle components in meta-analysis of gene-by-lifestyle interactions.
Xu H, Schwander K, Brown MR, Wang W, Waken RJ, Boerwinkle E, Cupples LA, de Las Fuentes L, van Heemst D, Osazuwa-Peters O, de Vries PS, van Dijk KW, Sung YJ, Zhang X, Morrison AC, Rao DC, Noordam R, Liu CT. Xu H, et al. Among authors: zhang x. Eur J Hum Genet. 2021 May;29(5):839-850. doi: 10.1038/s41431-021-00808-x. Epub 2021 Jan 26. Eur J Hum Genet. 2021. PMID: 33500576 Free PMC article.
Integrative clustering methods for multi-omics data.
Zhang X, Zhou Z, Xu H, Liu CT. Zhang X, et al. Wiley Interdiscip Rev Comput Stat. 2022 May-Jun;14(3):e1553. doi: 10.1002/wics.1553. Epub 2021 Feb 7. Wiley Interdiscip Rev Comput Stat. 2022. PMID: 35573155 Free PMC article.
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